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Search term: J-774A.1 cell

Results 1 - 7 of 7
EC Number
Source Tissue
Commentary
Reference
arachidonate 12-lipoxygenase
macrophage cell line
arachidonate 15-lipoxygenase
macrophage cell line
receptor protein-tyrosine kinase
in resting J774, scavenger receptor A is associated minimally with unphosphorylated (monomeric) Mertk
caspase-1
Salmonella enterica serovar typhimurium invades host macrophages and induces a unique caspase-1-dependent pathway of cell death termed pyroptosis, which is activated during bacterial infection in vivo. DNA cleavage during pyroptosis results from caspase-1-stimulated nuclease activity. Membrane pores between 1.1 and 2.4 nm in diameter form during pyroptosis of host cells and cause swelling and osmotic lysis. Pore formation requires host cell actin cytoskeleton rearrangements and caspase-1 activity, as well as the bacterial type III secretion system
Results 1 - 7 of 7