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EC Number
Source Tissue
Commentary
Reference
HIV-infected. Downregulation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase in hyposialylated HIV-infected T cells
enzyme activity is significantly elevated at 8 h after intradermal injection of carageenan or urate crystals, falling to normal levels by day 3
cell proliferation is directly correlated with GNE-expression and the cellular sialic acid concentration. Growth-related genes are differentially expressed in GNE-deficient embryonic stem cells compared to wild-type embryonic stem cells
enzyme activity is 18% of the activity found in normal livers
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