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EC Number
Source Tissue
Commentary
Reference
3.4.17.23
epithelium
of coronary and intrarenal vessels and renal tubuls
658455
3.4.17.23
heart ventricle
-
658455
,
658963
3.4.17.23
kidney
diabetic rats, 50% reduced enzyme content in renal tubules
658884
3.4.17.23
renal tubule
predominantly in proximal tubules, diabetic rats, 30% reduced enzyme content
658884
3.4.17.23
small intestine
-
658963
,
694170
,
762703
,
762787
3.4.17.23
colon
only moderate levels
659147
3.4.17.23
ovary
only moderate levels
659147
3.4.17.23
small intestine
only moderate levels
659147
3.4.17.23
aorta thoracica
chronic treatment with the AT1R antagonist almesartan induces a fivefold increase in ACE2 mRNA in the aorta which leads to a significant increase in aortic angiotensin(1-7) protein expression
667145
3.4.17.23
astrocyte
transcriptional regulation of ACE2 mRNA in astrocytes is dependent on the relative concentrations of both angiotensin II and angiotensin(17) as well as on interaction with their respective receptors
-
,
667146
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