EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
2.3.1.50 | serine C-palmitoyltransferase |
macrophage |
alveolar |
702430 |
2.3.1.50 | serine C-palmitoyltransferase |
macrophage |
bone marrowderived |
736559 |
2.3.1.50 | serine C-palmitoyltransferase |
macrophage |
mucosal from colon, lung, prostate, stomach, thyroid, uterus, vascular tissue |
487177 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
macrophage |
- |
736604 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
macrophage |
bone marrow-derived |
735644 |
2.3.1.97 | glycylpeptide N-tetradecanoyltransferase |
macrophage |
- |
719244 |
2.3.1.97 | glycylpeptide N-tetradecanoyltransferase |
macrophage |
alveolar |
703591 |
2.3.1.97 | glycylpeptide N-tetradecanoyltransferase |
macrophage |
intravascular, high NMT1 expression |
706890 |
2.3.1.B43 | protein-lysine desuccinylase (NAD+) |
macrophage |
SIRT5 and SIRT1/2 have opposite expression patterns and functions in macrophages, overview |
757084 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
macrophage |
- |
487830, 759544 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
macrophage |
monocyte-derived, presence of large amounts of TG2 on cell surface |
703983 |
2.3.2.2 | gamma-glutamyltransferase |
macrophage |
- |
736220 |
2.3.2.25 | N-terminal E2 ubiquitin-conjugating enzyme |
macrophage |
- |
759122 |
2.3.3.8 | ATP citrate synthase |
macrophage |
- |
735597 |
2.4.1.133 | xylosylprotein 4-beta-galactosyltransferase |
macrophage |
in the lesion site after spinal cord injury |
704802 |
2.4.1.212 | hyaluronan synthase |
macrophage |
HAS1 expression is shown in 55.7% of SIRPA-positive macrophages in stage III follicles |
702525 |
2.4.1.274 | glucosylceramide beta-1,4-galactosyltransferase |
macrophage |
alveolar mactrophage |
759227 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
macrophage |
high expression level |
687078 |
2.4.1.66 | procollagen glucosyltransferase |
macrophage |
peritoneal |
439149 |
2.4.1.80 | ceramide glucosyltransferase |
macrophage |
- |
706799 |
2.4.1.87 | N-acetyllactosaminide 3-alpha-galactosyltransferase |
macrophage |
- |
489469 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
macrophage |
- |
722182, 735872 |
2.4.2.31 | NAD+-protein-arginine ADP-ribosyltransferase |
macrophage |
- |
672357 |
2.4.2.4 | thymidine phosphorylase |
macrophage |
- |
638468 |
2.4.2.4 | thymidine phosphorylase |
macrophage |
very high expression level |
705495 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
macrophage |
- |
722730 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
macrophage |
- |
657703 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
macrophage |
differentiated monocyte-derived macrophages |
705676 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
macrophage |
excessive GM3 is synthesized in atherosclerotic lesions by macrophages and dendritic cells directly within the arterial walls |
657703 |
2.6.1.42 | branched-chain-amino-acid transaminase |
macrophage |
- |
758657 |
2.7.1.1 | hexokinase |
macrophage |
- |
737993 |
2.7.1.107 | diacylglycerol kinase (ATP) |
macrophage |
- |
675157 |
2.7.1.107 | diacylglycerol kinase (ATP) |
macrophage |
alveolar, isozymes DGKalpha and DGKzeta |
660679 |
2.7.1.134 | inositol-tetrakisphosphate 1-kinase |
macrophage |
bone marrow |
640814 |
2.7.1.137 | phosphatidylinositol 3-kinase |
macrophage |
the regulatory subunit p87PIKAP and the catalytic subunit p101 are both expressed |
674783 |
2.7.1.138 | ceramide kinase |
macrophage |
- |
-, 738824 |
2.7.1.138 | ceramide kinase |
macrophage |
bone marrow-derived macrophage, BMDM |
693223, 693454 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
macrophage |
- |
709350, 709980, 710351 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
macrophage |
bone marrow-derived macrophages |
722219 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
macrophage |
cell culture |
645036 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
macrophage |
cell culture, cell line J774.2 |
645036 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
macrophage |
dermal, moderate expression of PI3K-C2alpha and PI3K-C2beta |
645046 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
macrophage |
glomerular, moderate expression of PI3K-C2beta |
645046 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
macrophage |
isozyme PI3K-C2beta |
645046 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
macrophage |
PI3K-C2alpha and PI3K-C2beta |
645046 |
2.7.1.91 | sphingosine kinase |
macrophage |
- |
674843 |
2.7.1.91 | sphingosine kinase |
macrophage |
from bone marrow. N,N-dimethyl-D-erythro-sphingosine inhibits osteoclastogenesis a sphingosine kinase independently of sphingosine kinase |
689070 |
2.7.10.1 | receptor protein-tyrosine kinase |
macrophage |
- |
660727 |
2.7.10.1 | receptor protein-tyrosine kinase |
macrophage |
BAC1.2F5 macrophage cell line |
490192 |
2.7.10.1 | receptor protein-tyrosine kinase |
macrophage |
Ron is expressed on alveolar and peritoneal and monocyte-derived macrophages |
690303 |
2.7.10.2 | non-specific protein-tyrosine kinase |
macrophage |
- |
490151, 671253, 672781, 675097, 691455, 692647 |
2.7.10.2 | non-specific protein-tyrosine kinase |
macrophage |
from bone marrow |
662575 |
2.7.10.2 | non-specific protein-tyrosine kinase |
macrophage |
peritoneal and alveolar |
675097 |
2.7.10.2 | non-specific protein-tyrosine kinase |
macrophage |
peritoneal and splenic, and bone-marrow macrophages |
-, 675204 |
2.7.11.1 | non-specific serine/threonine protein kinase |
macrophage |
- |
742344 |
2.7.11.10 | IkappaB kinase |
macrophage |
- |
662570, 671920, 704912 |
2.7.11.10 | IkappaB kinase |
macrophage |
activated macrophages are significantly increased in Helicobacter pylori-infected gastric mucosa and are identified as being important cells with potent activation of NF-kappaB, which plays an important part in producing proinflammatory cytokines. Macrophage depletion by the administration of clodronate resulted in milder inflammation in gerbils infected with Helicobacter pylori |
692604 |
2.7.11.10 | IkappaB kinase |
macrophage |
alveolar and peritoneal |
662945 |
2.7.11.10 | IkappaB kinase |
macrophage |
bone marrow-derived or RAW-264.7 macrophages |
723569 |
2.7.11.15 | beta-adrenergic-receptor kinase |
macrophage |
- |
-, 673187 |
2.7.11.15 | beta-adrenergic-receptor kinase |
macrophage |
peritoneal macrophages, activation of Toll-like receptors significantly increases GRK2 expression in primary macrophages, mechanism, overview |
-, 689035 |
2.7.11.16 | G-protein-coupled receptor kinase |
macrophage |
- |
674691 |
2.7.11.16 | G-protein-coupled receptor kinase |
macrophage |
peritoneal macrophages, activation of Toll-like receptors selectively decreases arrestin-2 and GRK5 protein level in primary macrophages, mechanism, overview |
-, 689035 |
2.7.11.16 | G-protein-coupled receptor kinase |
macrophage |
peritoneal macrophages, activation of Toll-like receptors selectively decreases arrestin-2 and GRK6 protein level in primary macrophages, mechanism, overview |
-, 689035 |
2.7.11.21 | polo kinase |
macrophage |
transition of monocytes from peripheral blood to matrix bound macrophages is accompanied by increasing levels of Fnk with time in culture |
491303 |
2.7.11.24 | mitogen-activated protein kinase |
macrophage |
- |
491714, 664279, 681966, 691878 |
2.7.11.24 | mitogen-activated protein kinase |
macrophage |
p38 MAPK |
665798 |
2.7.11.25 | mitogen-activated protein kinase kinase kinase |
macrophage |
- |
663773 |
2.7.11.25 | mitogen-activated protein kinase kinase kinase |
macrophage |
TPL-2 and MEKK1 |
682954 |
2.7.11.30 | receptor protein serine/threonine kinase |
macrophage |
- |
762408 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
macrophage |
- |
760351 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
macrophage |
bone marrow-derived |
-, 739863 |
2.7.12.1 | dual-specificity kinase |
macrophage |
- |
761772 |
2.7.12.2 | mitogen-activated protein kinase kinase |
macrophage |
- |
491932, 663773 |
2.7.4.14 | UMP/CMP kinase |
macrophage |
- |
645160, 693063 |
2.7.4.21 | inositol-hexakisphosphate 5-kinase |
macrophage |
- |
-, 737654 |
2.7.7.15 | choline-phosphate cytidylyltransferase |
macrophage |
BAC1.2F5 cell line, SCF-1-dependent clone derived from the BAC1 line which originated from transfection of splenic adherent cells with SV40 |
642911 |
2.7.7.15 | choline-phosphate cytidylyltransferase |
macrophage |
CCTalpha is the major CCT isoform in macrophages |
691467 |
2.7.7.30 | fucose-1-phosphate guanylyltransferase |
macrophage |
- |
667231 |
2.7.7.86 | cyclic GMP-AMP synthase |
macrophage |
- |
738006 |
2.7.7.86 | cyclic GMP-AMP synthase |
macrophage |
primary and immortalized murine macrophages |
738791 |
2.7.7.96 | ADP-D-ribose pyrophosphorylase |
macrophage |
- |
684834 |
2.7.8.2 | diacylglycerol cholinephosphotransferase |
macrophage |
bacillus Calmette-Guerin induced rabbit |
644341 |
2.7.8.27 | sphingomyelin synthase |
macrophage |
- |
690656, 708149, 760628 |
2.7.8.27 | sphingomyelin synthase |
macrophage |
SMS1 is the major SMS |
737844 |
2.7.9.1 | pyruvate, phosphate dikinase |
macrophage |
- |
-, 738533 |
2.8.1.7 | cysteine desulfurase |
macrophage |
enzyme isoform Nfs1 |
671626 |
2.8.1.7 | cysteine desulfurase |
macrophage |
mitochondrial isoform of Nfs1 |
671626 |
2.8.2.29 | [heparan sulfate]-glucosamine 3-sulfotransferase 2 |
macrophage |
primary macrophages. HS3ST2 is highly expressed in non-activated macrophages |
760623 |
2.8.2.30 | [heparan sulfate]-glucosamine 3-sulfotransferase 3 |
macrophage |
primary macrophages. HS3ST3B is highly expressed in activated macrophages, highest after alternative stimulation (M2 polarization), while the enzyme is not detected in proinflammatory macrophages (M1) |
760623 |
2.8.2.4 | estrone sulfotransferase |
macrophage |
high expression |
723909 |
2.8.2.8 | [heparan sulfate]-glucosamine N-sulfotransferase |
macrophage |
high expression level of isozyme NDST2 |
704666 |
3.1.1.1 | carboxylesterase |
macrophage |
- |
691075 |
3.1.1.1 | carboxylesterase |
macrophage |
CES1, no expression of CES2 |
707570 |
3.1.1.111 | phosphatidylserine sn-1 acylhydrolase |
macrophage |
THP-1-derived macrophage |
753210 |
3.1.1.116 | sn-1-specific diacylglycerol lipase |
macrophage |
peritoneal macrophages |
761970 |
3.1.1.13 | sterol esterase |
macrophage |
- |
665963, 677459, 681075, 715834 |
3.1.1.13 | sterol esterase |
macrophage |
expressed at high levels in macrophages |
693179 |
3.1.1.13 | sterol esterase |
macrophage |
expressed at high levels in peritoneal macrophages |
693179 |
3.1.1.13 | sterol esterase |
macrophage |
highly expressed in macrophages |
715324 |