EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
2.1.1.17 | phosphatidylethanolamine N-methyltransferase |
hepatocyte |
- |
675185, 697842 |
2.1.1.17 | phosphatidylethanolamine N-methyltransferase |
hepatocyte |
high level of activity is expressed in defined extranuclear regions |
485180 |
2.1.1.17 | phosphatidylethanolamine N-methyltransferase |
hepatocyte |
primary culture |
696379 |
2.1.1.20 | glycine N-methyltransferase |
hepatocyte |
- |
677022 |
2.1.1.20 | glycine N-methyltransferase |
hepatocyte |
higher expression level in female than in male mice |
687011 |
2.1.1.355 | [histone H3]-lysine9 N-trimethyltransferase |
hepatocyte |
- |
752821 |
2.1.1.5 | betaine-homocysteine S-methyltransferase |
hepatocyte |
- |
671242, 687005, 704793, 733401, 755939 |
2.1.1.6 | catechol O-methyltransferase |
hepatocyte |
- |
702121 |
2.1.1.71 | phosphatidyl-N-methylethanolamine N-methyltransferase |
hepatocyte |
- |
-, 485554 |
2.1.2.5 | glutamate formimidoyltransferase |
hepatocyte |
- |
651207 |
2.1.3.3 | ornithine carbamoyltransferase |
hepatocyte |
- |
757879 |
2.1.3.3 | ornithine carbamoyltransferase |
hepatocyte |
primary |
720095 |
2.1.3.3 | ornithine carbamoyltransferase |
hepatocyte |
primary hepatocytes |
-, 736014 |
2.3.1.137 | carnitine O-octanoyltransferase |
hepatocyte |
- |
486301 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
hepatocyte |
- |
660676, 702433, 736424, 757868 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
hepatocyte |
primary hepatocyte |
736424 |
2.3.1.199 | very-long-chain 3-oxoacyl-CoA synthase |
hepatocyte |
- |
744399 |
2.3.1.20 | diacylglycerol O-acyltransferase |
hepatocyte |
- |
735573 |
2.3.1.21 | carnitine O-palmitoyltransferase |
hepatocyte |
- |
684341, 688981 |
2.3.1.22 | 2-acylglycerol O-acyltransferase |
hepatocyte |
- |
735755, 757542 |
2.3.1.22 | 2-acylglycerol O-acyltransferase |
hepatocyte |
primary |
735610 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
hepatocyte |
- |
675007, 757194 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
hepatocyte |
primary |
756896 |
2.3.1.24 | sphingosine N-acyltransferase |
hepatocyte |
- |
-, 754040, 754625, 756688 |
2.3.1.26 | sterol O-acyltransferase |
hepatocyte |
- |
486677, 486706, 684882, 685611, 736702, 736719 |
2.3.1.26 | sterol O-acyltransferase |
hepatocyte |
primary |
-, 736580 |
2.3.1.26 | sterol O-acyltransferase |
hepatocyte |
two different forms of the enzyme are present, ACAT1 and ACAT2 |
486706, 486708 |
2.3.1.48 | histone acetyltransferase |
hepatocyte |
primary |
671237 |
2.3.1.5 | arylamine N-acetyltransferase |
hepatocyte |
- |
755741 |
2.3.1.57 | diamine N-acetyltransferase |
hepatocyte |
- |
701662 |
2.3.1.57 | diamine N-acetyltransferase |
hepatocyte |
primary |
736007 |
2.3.1.65 | bile acid-CoA:amino acid N-acyltransferase |
hepatocyte |
- |
673916, 706769 |
2.3.1.B41 | protein-long-chain fatty-acyl-lysine deacylase (NAD+) |
hepatocyte |
- |
757644 |
2.3.1.B43 | protein-lysine desuccinylase (NAD+) |
hepatocyte |
- |
739069, 756522 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
hepatocyte |
- |
487830 |
2.3.3.10 | hydroxymethylglutaryl-CoA synthase |
hepatocyte |
- |
488104, 657803 |
2.3.3.8 | ATP citrate synthase |
hepatocyte |
ACLY deficiency in hepatocytes protects from hepatic steatosis and dyslipidemia |
758267 |
2.4.1.1 | glycogen phosphorylase |
hepatocyte |
- |
-, 660037, 672580, 685004, 735773 |
2.4.1.1 | glycogen phosphorylase |
hepatocyte |
primary culture |
702627 |
2.4.1.1 | glycogen phosphorylase |
hepatocyte |
primary hepatocyte |
675593 |
2.4.1.1 | glycogen phosphorylase |
hepatocyte |
stimulation and inhibition of glycogen synthesis in hepatocytes by serotonergic mechanisms. The former effects are associated with the inactivation of phosphorylase and are counteracted by atypical antipsychotic drugs that cause hepatic insulin resistance. Antagonism of hepatic serotonergic mechanisms may be a component of the hepatic dysregulation caused by antipsychotic drugs that predispose to type 2 diabetes |
686315 |
2.4.1.11 | glycogen(starch) synthase |
hepatocyte |
- |
488443, 488450, 671617, 676098 |
2.4.1.11 | glycogen(starch) synthase |
hepatocyte |
primary culture |
658875 |
2.4.1.11 | glycogen(starch) synthase |
hepatocyte |
reduction in glucose production in primary hepatocytes by the overexpression of the mutant GYS2. The elevation of liver glycogen synthase activity in primary hepatocytes reduces glucose production by shunting gluconeogenic precursors into glycogen rather than by stimulating direct glucose incorporation into glycogen |
684689 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
hepatocyte |
different expression level in fetal and adult hepatocytes |
638227 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
hepatocyte |
primary |
638227 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
hepatocyte |
very low amount |
638223, 638227 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
hepatocyte |
- |
639533 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
hepatocyte |
- |
704793 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
hepatocyte |
primary |
659759 |
2.4.1.17 | glucuronosyltransferase |
hepatocyte |
- |
673287, 703403 |
2.4.1.17 | glucuronosyltransferase |
hepatocyte |
a low basal level of UGT1A5 expression in cultured hepatocytes. Treatment with rifampicin or 3-methylcholanthrene increases the level of UGT1A5 mRNA |
675594 |
2.4.1.17 | glucuronosyltransferase |
hepatocyte |
primary culture |
692053 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
hepatocyte |
- |
686836 |
2.4.1.87 | N-acetyllactosaminide 3-alpha-galactosyltransferase |
hepatocyte |
- |
758548 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
hepatocyte |
release of NAMPT enzyme into the cell culture supernatant occurs constitutively. In primary hepatocytes, secretion within 24 h is far higher than the cellular content, but is neither influenced by inhibitors of secretion nor by glucose, insulin or TNFalpha. In primary human hepatocytes, secreted NAMPT is less active than intracellular enzyme |
702085 |
2.4.2.19 | nicotinate-nucleotide diphosphorylase (carboxylating) |
hepatocyte |
- |
760157 |
2.4.2.28 | S-methyl-5'-thioadenosine phosphorylase |
hepatocyte |
- |
737123 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
hepatocyte |
- |
637284 |
2.5.1.18 | glutathione transferase |
hepatocyte |
- |
722273 |
2.5.1.18 | glutathione transferase |
hepatocyte |
primary |
673913 |
2.5.1.21 | squalene synthase |
hepatocyte |
- |
697143 |
2.5.1.21 | squalene synthase |
hepatocyte |
primary |
721838 |
2.5.1.6 | methionine adenosyltransferase |
hepatocyte |
- |
687010 |
2.5.1.6 | methionine adenosyltransferase |
hepatocyte |
adult quiescent hepatocyte |
687118 |
2.5.1.6 | methionine adenosyltransferase |
hepatocyte |
in cultured hepatocytes MAT1A expression falls and MAT2A is induced when S-adenosyl-L-methionine level falls, which can be prevented by exogenous S-adenosyl-L-methionine |
675169 |
2.5.1.61 | hydroxymethylbilane synthase |
hepatocyte |
- |
709334 |
2.6.1.1 | aspartate transaminase |
hepatocyte |
- |
759587 |
2.6.1.42 | branched-chain-amino-acid transaminase |
hepatocyte |
- |
640019, 640037 |
2.6.1.43 | aminolevulinate transaminase |
hepatocyte |
- |
640059 |
2.6.1.44 | alanine-glyoxylate transaminase |
hepatocyte |
- |
640075, 640086, 758712 |
2.6.1.5 | tyrosine transaminase |
hepatocyte |
- |
702386 |
2.6.1.51 | serine-pyruvate transaminase |
hepatocyte |
- |
640138 |
2.6.1.88 | methionine transaminase |
hepatocyte |
- |
-, 759460 |
2.7.1.1 | hexokinase |
hepatocyte |
- |
663393, 704479 |
2.7.1.1 | hexokinase |
hepatocyte |
153-306 times higher overexpression in rat AS-30D hepatoma cells than in normal freshly isolated rat hepatocytes |
673541 |
2.7.1.105 | 6-phosphofructo-2-kinase |
hepatocyte |
- |
-, 640281, 640294, 737752 |
2.7.1.105 | 6-phosphofructo-2-kinase |
hepatocyte |
coordinate roles for glucokinase and PFK2 in the elevated hepatic glycolysis in fa/fa rats |
671260 |
2.7.1.105 | 6-phosphofructo-2-kinase |
hepatocyte |
primary culture |
661569 |
2.7.1.105 | 6-phosphofructo-2-kinase |
hepatocyte |
primary culture, treated and untreated with adenoviral vector to overexpress wild-type PFK-2 and mutant PKF2-M lacking Ser-32 phosphorylation site |
684366 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
hepatocyte |
primary |
663233 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
hepatocyte |
vasopressin-stimulated cells |
640731 |
2.7.1.137 | phosphatidylinositol 3-kinase |
hepatocyte |
- |
640873, 640883 |
2.7.1.151 | inositol-polyphosphate multikinase |
hepatocyte |
primary |
663233 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
hepatocyte |
- |
761780 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
hepatocyte |
- |
761194 |
2.7.1.20 | adenosine kinase |
hepatocyte |
- |
738347 |
2.7.1.28 | triokinase |
hepatocyte |
primary |
-, 759025 |
2.7.1.30 | glycerol kinase |
hepatocyte |
- |
761058 |
2.7.1.30 | glycerol kinase |
hepatocyte |
primary culture of |
641313 |
2.7.1.31 | glycerate 3-kinase |
hepatocyte |
- |
673281 |
2.7.1.32 | choline kinase |
hepatocyte |
- |
663274 |
2.7.1.40 | pyruvate kinase |
hepatocyte |
- |
693950 |
2.7.10.1 | receptor protein-tyrosine kinase |
hepatocyte |
- |
690303 |
2.7.10.1 | receptor protein-tyrosine kinase |
hepatocyte |
primary cells |
661848 |
2.7.11.1 | non-specific serine/threonine protein kinase |
hepatocyte |
- |
742127 |
2.7.11.1 | non-specific serine/threonine protein kinase |
hepatocyte |
primary |
-, 723027 |
2.7.11.10 | IkappaB kinase |
hepatocyte |
- |
662516 |
2.7.11.11 | cAMP-dependent protein kinase |
hepatocyte |
- |
762105 |
2.7.11.13 | protein kinase C |
hepatocyte |
- |
703109 |