EC Number   |
Recommended Name |
Source Tissue |
Reference |
|---|
   1.11.1.16 | versatile peroxidase |
heart |
- |
764524 |
 1.11.1.20 | prostamide/prostaglandin F2alpha synthase |
heart |
- |
687797 |
| 1.11.1.20 | prostamide/prostaglandin F2alpha synthase |
heart |
activity is the highest in spinal cord and brain followed by thymus, adrenal gland, heart, and genital organs |
687797 |
| 1.11.1.24 | thioredoxin-dependent peroxiredoxin |
heart |
- |
686285, 700109, 725050 |
| 1.11.1.24 | thioredoxin-dependent peroxiredoxin |
heart |
0.0013 mg Prx I per mg of soluble protein Prx I, 0.002 mg Prx II per mg of soluble protein, 0.0033 mg Prx III per mg of soluble protein, 0.0005 mg Prx V per mg of soluble protein and 0.0003 mg Prx VI per mg of soluble protein |
655756 |
| 1.11.1.5 | cytochrome-c peroxidase |
heart |
- |
672298, 672308, 672309 |
| 1.11.1.6 | catalase |
heart |
- |
725156, 725932 |
| 1.11.1.6 | catalase |
heart |
activity increased significantly in the diazinon treated group compared with the control group |
672966 |
| 1.11.1.6 | catalase |
heart |
highest levels of transcripts in hepatopancreas, followed by a little lower expression in hemocytes and moderate expression in the tissues of brain, eyestalk, gill, intestine and muscle, with the lowest expression in the heart |
744948 |
| 1.11.1.7 | peroxidase |
heart |
- |
698048 |
| 1.11.1.7 | peroxidase |
heart |
thioreoxin peroxidase |
439745 |
| 1.11.1.7 | peroxidase |
heart |
VPO2 is highly expressed in heart |
698048 |
| 1.11.1.9 | glutathione peroxidase |
heart |
- |
658792, 695410 |
| 1.11.1.9 | glutathione peroxidase |
heart |
highest levels of transcripts in hepatopancreas, followed by a little lower expression in hemocytes and moderate expression in the tissues of brain, eyestalk, gill, intestine and muscle, with the lowest expression in the heart |
744948 |
| 1.11.1.9 | glutathione peroxidase |
heart |
highest mRNA expression in ovary, followed by pyloric ceca, heart, liver and brain |
724102 |
| 1.11.1.9 | glutathione peroxidase |
heart |
highest mRNA expression in pyloric ceca, followed by brain, heart and liver |
724102 |
| 1.11.1.9 | glutathione peroxidase |
heart |
overexpression of glutathione peroxidase attenuates myocardial remodeling and preserves diastolic function in diabetic heart |
671245 |
| 1.11.1.9 | glutathione peroxidase |
heart |
weak expression of pGPx |
672988 |
| 1.13.11.19 | cysteamine dioxygenase |
heart |
- |
396418 |
| 1.13.11.19 | cysteamine dioxygenase |
heart |
high activity |
687595 |
| 1.13.11.31 | arachidonate 12-lipoxygenase |
heart |
- |
-, 704901, 741573 |
| 1.13.11.31 | arachidonate 12-lipoxygenase |
heart |
expression of 12/15-LOX pathway is upregulated in the diabetic heart |
-, 742346 |
| 1.13.11.33 | arachidonate 15-lipoxygenase |
heart |
- |
-, 701636, 726871 |
| 1.13.11.33 | arachidonate 15-lipoxygenase |
heart |
expression of 12/15-LOX pathway is upregulated in the diabetic heart |
-, 742346 |
| 1.13.11.34 | arachidonate 5-lipoxygenase |
heart |
- |
686557, 742314 |
| 1.13.11.5 | homogentisate 1,2-dioxygenase |
heart |
expression of HGO gene |
439388 |
| 1.13.11.52 | indoleamine 2,3-dioxygenase |
heart |
- |
665457 |
| 1.13.11.63 | beta-carotene 15,15'-dioxygenase |
heart |
- |
744160 |
| 1.13.11.63 | beta-carotene 15,15'-dioxygenase |
heart |
beta-carotene-15,15'-dioxygenase (BCO1) protein is not expressed in adult hearts of male wild-type mice |
743991 |
| 1.13.11.71 | carotenoid-9',10'-cleaving dioxygenase |
heart |
- |
-, 744160 |
| 1.13.11.71 | carotenoid-9',10'-cleaving dioxygenase |
heart |
low abundance of mRNA |
719806 |
| 1.14.11.1 | gamma-butyrobetaine dioxygenase |
heart |
- |
439296, 676337, 697453, 699163 |
| 1.14.11.16 | peptide-aspartate beta-dioxygenase |
heart |
- |
439251 |
| 1.14.11.2 | procollagen-proline 4-dioxygenase |
heart |
- |
439239, 439242, 439243, 659235 |
| 1.14.11.2 | procollagen-proline 4-dioxygenase |
heart |
embryo |
439200 |
| 1.14.11.2 | procollagen-proline 4-dioxygenase |
heart |
expression of enzyme alpha-I and alpha-II subunit mRNAs |
439242 |
| 1.14.11.2 | procollagen-proline 4-dioxygenase |
heart |
expression of enzyme alpha-I and alpha-II subunits mRNAs |
439239 |
| 1.14.11.2 | procollagen-proline 4-dioxygenase |
heart |
the type I enzyme is the main enzyme form |
439243 |
| 1.14.11.29 | hypoxia-inducible factor-proline dioxygenase |
heart |
- |
741826 |
| 1.14.11.29 | hypoxia-inducible factor-proline dioxygenase |
heart |
expression level of of HIF-P4H-3 mRNA is highest in the adult heart, brain, placenta, lung, and skeletal muscle and in the fetal heart, spleen, and skeletal muscle |
659235 |
| 1.14.11.29 | hypoxia-inducible factor-proline dioxygenase |
heart |
the levels of HIF-P4H-2 mRNA expression is highest in the adult heart, brain, lung, and liver and in the fetal brain, heart, spleen, and skeletal muscle |
659235 |
| 1.14.11.4 | procollagen-lysine 5-dioxygenase |
heart |
- |
657744, 659548, 675031, 675766, 724792 |
| 1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
heart |
3.3fold increase in mRNA after 6 h of hypoxia |
684929 |
| 1.14.11.7 | procollagen-proline 3-dioxygenase |
heart |
isozyme P3H1 |
697189 |
| 1.14.11.7 | procollagen-proline 3-dioxygenase |
heart |
isozyme P3H2 |
697189 |
| 1.14.11.7 | procollagen-proline 3-dioxygenase |
heart |
isozyme P3H3 |
697189 |
| 1.14.11.8 | trimethyllysine dioxygenase |
heart |
- |
671302, 675029 |
| 1.14.13.39 | nitric-oxide synthase (NADPH) |
heart |
- |
671278, 744948 |
| 1.14.13.39 | nitric-oxide synthase (NADPH) |
heart |
eNOS |
687358 |
| 1.14.13.8 | flavin-containing monooxygenase |
heart |
- |
673313 |
| 1.14.14.154 | sterol 14alpha-demethylase |
heart |
- |
673147 |
| 1.14.14.18 | heme oxygenase (biliverdin-producing) |
heart |
- |
438244, 438257, 674063 |
| 1.14.14.19 | steroid 17alpha-monooxygenase |
heart |
- |
705401 |
| 1.14.14.24 | vitamin D 25-hydroxylase |
heart |
low expression |
717769 |
| 1.14.14.32 | 17alpha-hydroxyprogesterone deacetylase |
heart |
- |
734569 |
| 1.14.14.94 | leukotriene-B4 20-monooxygenase |
heart |
CYP4F11 |
660409 |
| 1.14.15.15 | cholestanetriol 26-monooxygenase |
heart |
- |
736710 |
| 1.14.15.16 | vitamin D3 24-hydroxylase |
heart |
- |
714836 |
| 1.14.15.18 | calcidiol 1-monooxygenase |
heart |
- |
737985 |
| 1.14.15.3 | alkane 1-monooxygenase |
heart |
- |
671219 |
| 1.14.15.4 | steroid 11beta-monooxygenase |
heart |
- |
686286 |
| 1.14.15.4 | steroid 11beta-monooxygenase |
heart |
cardiac tissue from several rat models of cardiovascular pathology, low constitutive expression, which seems to be of no physiologic relevance |
673345 |
| 1.14.16.2 | tyrosine 3-monooxygenase |
heart |
- |
438686, 701155, 745402 |
| 1.14.16.2 | tyrosine 3-monooxygenase |
heart |
2fold activity under cold stress. Injection of the angiotensin converting enzyme inhibitor enalapril malate prevented the increase of tyrosine hydroxylase under cold stress |
672960 |
| 1.14.16.2 | tyrosine 3-monooxygenase |
heart |
increase in tyrosine hydroxylase protein levels and tyrosine hydroxylase enzyme activity might contribute to the enhanced noradrenergic activity in the heart in response to morphine withdrawam |
658658 |
| 1.14.16.4 | tryptophan 5-monooxygenase |
heart |
low levels of TPH-2 |
705929 |
| 1.14.16.5 | alkylglycerol monooxygenase |
heart |
- |
688220 |
| 1.14.17.1 | dopamine beta-monooxygenase |
heart |
- |
727633 |
| 1.14.17.1 | dopamine beta-monooxygenase |
heart |
lowest level of all tissues |
702945 |
| 1.14.17.3 | peptidylglycine monooxygenase |
heart |
- |
438586, 648703, 657678, 658458 |
| 1.14.17.3 | peptidylglycine monooxygenase |
heart |
atrium |
438579, 438583 |
| 1.14.17.3 | peptidylglycine monooxygenase |
heart |
myoblast, H9c2 cells |
438588 |
| 1.14.17.3 | peptidylglycine monooxygenase |
heart |
predominantly membrane-associated, bifunctional enzyme |
438583 |
| 1.14.17.3 | peptidylglycine monooxygenase |
heart |
ventricle |
438583 |
| 1.14.18.2 | CMP-N-acetylneuraminate monooxygenase |
heart |
weak activity |
639329 |
| 1.14.19.1 | stearoyl-CoA 9-desaturase |
heart |
- |
688769, 714663 |
| 1.14.19.1 | stearoyl-CoA 9-desaturase |
heart |
exclusively expressed in heart, no repression by dietary polyunsaturated fatty acids, induction in SCD1-deficient animals |
659244 |
| 1.14.19.1 | stearoyl-CoA 9-desaturase |
heart |
isoforms SCD-1 and SCD-4 |
695472 |
| 1.14.19.1 | stearoyl-CoA 9-desaturase |
heart |
isozyme SCD1, SCD2, and SCD4 |
684339 |
| 1.14.19.1 | stearoyl-CoA 9-desaturase |
heart |
isozyme SCD4 is expressed mainly in the heart |
746542 |
| 1.14.19.1 | stearoyl-CoA 9-desaturase |
heart |
low expression level of isozyme SCD1 |
688769 |
| 1.14.19.1 | stearoyl-CoA 9-desaturase |
heart |
SCD4 isoform |
673285 |
| 1.14.19.3 | acyl-CoA 6-desaturase |
heart |
- |
659836 |
| 1.14.19.30 | acyl-lipid (8-3)-desaturase |
heart |
- |
746201 |
| 1.14.19.30 | acyl-lipid (8-3)-desaturase |
heart |
most abundant |
734131 |
| 1.14.19.44 | acyl-CoA (8-3)-desaturase |
heart |
most abundant in the heart |
734131 |
| 1.14.19.47 | acyl-lipid (9-3)-desaturase |
heart |
highest DELTA6fad mRNA expression is detected in liver followed by brain, with lower expression in other tissues including intestine, eye, muscle, adipose, heart kidney and gill, and lowest expression in stomach and spleen |
746261 |
| 1.14.99.38 | cholesterol 25-monooxygenase |
heart |
- |
658159, 700999, 727109 |
| 1.14.99.60 | 3-demethoxyubiquinol 3-hydroxylase |
heart |
COQ7 is highly expressed in tissues with high energy demand such as heart, muscle, liver, and kidney |
746956 |
| 1.15.1.1 | superoxide dismutase |
heart |
- |
438089, 727563, 744746, 746564 |
| 1.15.1.1 | superoxide dismutase |
heart |
Cu,Zn-SOD, in vessels, including endothelium |
-, 438181 |
| 1.15.1.1 | superoxide dismutase |
heart |
cytoplasmic manganese SOD |
745093 |
| 1.15.1.1 | superoxide dismutase |
heart |
Mn-SOD, endothelium |
-, 438181 |
| 1.16.1.8 | [methionine synthase] reductase |
heart |
in vivo quantitative real-time PCR analysis of MTRR mRNA in cardiac tissue samples from congenital heart disease patients, overview |
727334 |
| 1.17.1.4 | xanthine dehydrogenase |
heart |
- |
644557, 644558 |
| 1.17.1.4 | xanthine dehydrogenase |
heart |
high rate of dehydrogenase activity |
644557, 644558 |
| 1.17.1.4 | xanthine dehydrogenase |
heart |
low enzyme activity |
706471 |
| 1.17.1.4 | xanthine dehydrogenase |
heart |
only oxidase type O form |
644582 |
| 1.17.3.2 | xanthine oxidase |
heart |
- |
685983, 687898 |
| 1.17.3.2 | xanthine oxidase |
heart |
enzyme expression is increased in the failing heart |
688764 |
