EC Number |
kcat/KM Value [1/mMs-1] |
kcat/KM Value Maximum [1/mMs-1] |
Substrate |
Reference |
---|
1.1.1.184 | 0.0013 |
- |
NADPH |
isoform Cbr3, at pH 7.0 and 37°C |
760967 |
1.1.1.184 | 0.035 |
- |
doxorubicin |
isoform Cbr3, at pH 7.0 and 37°C |
760967 |
1.1.1.184 | 0.12 |
- |
doxorubicin |
isoform Cbr1, at pH 7.0 and 37°C |
760967 |
1.1.1.184 | 0.17 |
- |
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone |
enzyme modified by S-nitrosoglutathione, pH 7.4, 37°C |
724718 |
1.1.1.184 | 0.25 |
- |
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone |
wild-type, pH 7.4, 37°C |
724718 |
1.1.1.184 | 0.36 |
- |
NADPH |
isoform Cbr1, at pH 7.0 and 37°C |
760967 |
1.1.1.184 | 0.99 |
- |
2,3-Pentanedione |
pH 7.0, 25°C |
724046 |
1.1.1.184 | 1.3 |
- |
2-Pentanone |
pH 7.5, 37°C |
724899 |
1.1.1.184 | 1.4 |
- |
2,3-Butanediol |
pH 7.5, 37°C |
724899 |
1.1.1.184 | 1.72 |
- |
S-nitrosoglutathione |
mutant D236A/K238P/D239K/S240A/I241T/R242K/T243S/V244P, pH 7.4, temperature not specified in the publication |
724714 |