7.6.2.5 | physiological function |
HmuT from Corynebacterium glutamicum is a heme-binding protein in an ABC-type heme transporter system, HmuTUV. The Corynebacterium glutamicum heme acquisition system consists of HtaA, HtaB, and HmuTUV. Heme is transported into the cytoplasm by this ABC transporter. Heme is captured by the membrane-anchored heme-binding proteins, HtaA and HtaB, and is transferred to HmuT, which is a heme-binding protein for the ABC-type heme transporter HmuUV. Pathogenic bacteria use heme as an iron source partly because heme is the most abundant iron species in their host |
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