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EC Number	General Information	Commentary	Reference
6.3.2.9	metabolism	the enzyme is involved in the peptidoglycan biosynthesis	746203
6.3.2.9	more	conformational changes of MurD occur upon ligand binding. Upon binding of ATP and UDP-N-acetyl-alpha-D-muramoyl-L-alanine, there is a closing rotation of the C-terminal domain, which does not occur before ATP is bound, targeted molecular dynamics simulation	746203
6.3.2.9	physiological function	MurD catalyzes the addition of D-glutamic acid to UDP-MurNAc-L-Ala, generating the dipeptide moiety L-Ala-D-Glu in peptidoglycan biosynthesis	746203

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Release 2023.1 (January 2023)