EC Number   |
General Information |
Reference |
|---|
   6.3.2.24 | malfunction |
TyrRS knockdown of PC12 cells with a small interfering RNA (siRNA) in the presence of 1.6mM tyrosine, arginine, proline, or tryptophan significantly reduces the level of KTP, but not those of tyrosine-tyrosine, tyrosine-proline, or tyrosine-tryptophan. siRNA treatment does not affect cell survival or proliferation |
745971 |
| 6.3.2.24 | malfunction |
when arginine is administered 2 h prior to brain dissection, the KTP levels in these regions plus olfactory bulb significantly increase, although basal brain KTP levels remain relatively even |
-, 745971 |
| 6.3.2.24 | physiological function |
tyrosyl-tRNA synthetase is a potential kyotorphin synthetase (i.e. tyrosine-arginine ligase, EC 6.3.2.24) in mammals, positive correlation across brain regions between TyrRS expression and arginine-accelerated KTP production |
-, 745971 |
| 6.3.2.24 | physiological function |
TyrRS knockdown of PC12 cells with siRNA in the presence of 1.6 mM tyrosine, arginine, proline, or tryptophan significantly reduces the level of product kyotorphin, but not those of tyrosine-tyrosine, tyrosine-proline, or tyrosine-tryptophan. siRNA treatment does not affect cell survival or proliferation |
745971 |
