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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 6.2.1.42malfunction deletion of fadD19 completely blocks side chain degradation of C-24 branched sterols but not that of cholesterol -, 729024
Display the reaction diagram Show all sequences 6.2.1.42metabolism the enzyme essential for degradation of C-24 branched sterol side chains -, 729024
Display the reaction diagram Show all sequences 6.2.1.42metabolism the enzyme plays an essential role in C-24 branched side chain sterol degradation, overview -, 745820
Display the reaction diagram Show all sequences 6.2.1.42physiological function the enzyme encoded by gene fadD19 plays a role in the degradation process of the side chain of cholesterol and beta-sitosterol, but is not essential for viability. FadD19 is required in the initial step of the biodegradation of C-24 branched sterol side chains in Mycobacterium smegmatis mc2155, like beta-sitosterol, but not those carrying a straight chain, like cholesterol. The enzyme has an essential role of FadD19 in the early step of beta-sitosterol degradation -, 745820
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