EC Number   |
General Information |
Reference |
|---|
  5.6.1.9 | physiological function |
FldI is an oxygen-sensitive initiator protein required for initial activation of phenyllactate dehydratase, EC 4.2.1.175. In the oxidized state, FldI exhibits significant ATPase activity, which appears to be essential for unidirectional electron transfer |
754768 |
| 5.6.1.9 | physiological function |
operon HgdCAB encodes 2-hydroxyglutaryl-CoA dehydratase HgdAB and initiator component A, HgdC |
753474 |
| 5.6.1.9 | physiological function |
the reduced activator HadI transfers one electron to the dehydratase concomitant with hydrolysis of ATP. The thus activated dehydratase catalyzes about 10000 dehydration turnovers until the enzyme becomes inactive. Adding activator, ATP, MgCl2, dithionite and dithioerythritol reactivates the enzyme |
753540 |
