EC Number   |
General Information |
Reference |
|---|
    5.4.99.7 | evolution |
the enzyme belongs to the product-specific oxidosqualene cyclases (OSCs) that constitute a significant metabolic branch point which is the initial step of triterpene chemical diversity |
749038 |
| 5.4.99.7 | evolution |
the enzyme belongs to the terpene cyclase/mutase superfamily of enzymes |
749433 |
| 5.4.99.7 | metabolism |
oxidosqualene-lanosterol cyclase is a key enzyme in the biosynthesis of cholesterol |
728192 |
| 5.4.99.7 | metabolism |
part of cholesterol synthesis pathway |
697143 |
| 5.4.99.7 | metabolism |
phytosterol homeostasis may be maintained in leaves through diversion of intermediates into glycoalkaloid biosynthesis, whereas in tuber flesh, excess intermediates are catalyzed by tuber-specific StLAS-like, resulting in low tuber glycoalkaloids. The enzyme as product-specific oxidosqualene cyclase constitutes a significant metabolic branch point which is the initial step of triterpene chemical diversity |
749038 |
| 5.4.99.7 | metabolism |
the enzyme as product-specific oxidosqualene cyclase constitutes a significant metabolic branch point which is the initial step of triterpene chemical diversity |
749038 |
| 5.4.99.7 | more |
determination of ganoderic acids and lanosterol in mycelia |
-, 748885 |
| 5.4.99.7 | more |
H232 mutant energy profiles compared to the wild-type enzyme, overview |
728192 |
| 5.4.99.7 | more |
structure-function-mechanism relationships, overview |
728421 |
| 5.4.99.7 | physiological function |
functional role of the Cys703 residue in stabilizing the bicyclic C-8 cation and the rearranged intermediate or interacting with Phe699 |
727106 |
