EC Number   |
General Information |
Reference |
|---|
   5.1.3.34 | evolution |
the MgdE protein contains a fatty acid hydroxylase domain and a Rossmann-fold domain and belongs to the short-chain dehydrogenase/reductase family of proteins. The Rossmann fold functions as an oxidoreductase domain. In some cyanobacteria, such as Prochlorococcus, MgdE lacks the hydroxylase domain |
-, 735181 |
| 5.1.3.34 | evolution |
the MgdE protein is a member of NAD-dependent oxidoreductases. Mechanisms of monogalactosyldiacylglycerol synthesis in cyanobacteria, overview |
-, 734885 |
| 5.1.3.34 | malfunction |
knockout mutants of mgdE in Synechocystis sp. PCC 6803 lack both monogalactosyldiacylglycerol and digalactosyldiacylglycerol and accumulated monoglucosyldiacylglycerol. The mutants possess thylakoid membranes and show normal maximal photosynthetic activity, albeit with reduced utilization of light energy. Cyanobacterial mutants in which the gene is disrupted still grow photosynthetically, indicating that galactolipids are not essential for either oxygenic photosynthesis or the development of the thylakoid membrane structure. Phenotype, overview |
735181 |
| 5.1.3.34 | metabolism |
all the analyzed cyanobacteria contain monoglucosyldiacylglycerol, which is converted to monogalactosyldiacylglycerol, and suggest that an alternative epimerase is required for monogalactosyldiacylglycerol synthesis in these cyanobacteria |
-, 734885 |
| 5.1.3.34 | metabolism |
in cyanobacteria, monogalactosyldiacylglycerol is synthesized via monoglucosyldiacylglycerol. The galactolipids monogalactosyldiacylglycerol and digalactosyldiacylglycerol dominate the thylakoid membranes of the oxygenic photosynthetic organisms, both types of galactolipids are bound in the interior of photosystem complexes |
735181 |
| 5.1.3.34 | more |
monogalactosyldiacylglycerol is ubiquitous in the photosynthetic membranes of cyanobacteria and chloroplasts. It is synthesized by galactosylation of diacylglycerol in the chloroplasts, whereas it is produced by epimerization of monoglucosyldiacylglycerol in at least several cyanobacteria |
-, 734885 |
| 5.1.3.34 | more |
monogalactosyldiacylglycerol is ubiquitous in the photosynthetic membranes of cyanobacteria and chloroplasts. It is synthesized by galactosylation of diacylglycerol in the chloroplasts, whereas it is produced by epimerization of monoglucosyldiacylglycerol in at least several cyanobacteria. The N-terminal fatty acid hydroxylase domain is lacking in the MgdE protein of Prochlorococcus marinus. The monoglucosyldiacylglycerol level is very low in Prochlorococcus marinus, but it is about 1/50 of that of monogalactosyldiacylglycerol in most cyanobacteria |
-, 734885 |
| 5.1.3.34 | physiological function |
the enzyme is required for synthesis of monogalactosyldiacylglycerol, which is used as functional component of thylakoid membranes. But oxygenic photosynthesis is not absolutely dependent on galactolipids |
-, 735181 |
