EC Number |
General Information |
Reference |
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5.1.3.18 | malfunction |
silencing of the two GME genes in tomato leaves results in approximately a 60% decrease in terminal L-galactose content in the side chain A of rhamnogalacturonan II as well as in a lower capacity of rhamnogalacturonan II to perform in muro cross-linking |
715659 |
5.1.3.18 | metabolism |
GDP-D-mannose 3',5'-epimerase catalyses a committed step in ascorbic acid biosynthesis |
728796 |
5.1.3.18 | metabolism |
GME is a central enzyme of the major ascorbate biosynthesis pathway in higher plants, it play a key role in the regulation of ascorbate biosynthesis in plants, adjusting the balance between ascorbate and cell-wall monosaccharide biosynthesis. GDP-D-mannose synthesis is the initial step in the pathway of ascorbate biosynthesis, and GDP-D-mannose is also a known precursor for the synthesis of D-mannose, L-fucose and L-galactose, and therefore for hemicelluloses such s the (galacto)glucomannans and for the pectin rhamnogalacturonan II |
706239 |
5.1.3.18 | metabolism |
the enzyme is involved in the l-galactose pathway |
725792 |
5.1.3.18 | physiological function |
GDP-D-mannose 3',5'-epimerase catalyses a committed step in ascorbic acid biosynthesis, ascorbic acid plays important roles in antioxidative defenses against environmental stresses in higher plants |
728796 |
5.1.3.18 | physiological function |
transgenic plants over-expressing isoform GME1 exhibit a significant increase in total ascorbic acid in leaves and red fruits compared with wild type plants and improved tolerance to methyl viologen, cold, and salt stresses |
716504 |
5.1.3.18 | physiological function |
transgenic plants over-expressing isoform GME2 exhibit a significant increase in total ascorbic acid in leaves and red fruits compared with wild type plants and improved tolerance to methyl viologen, cold, and salt stresses |
716504 |