EC Number   |
General Information |
Reference |
|---|
    5.1.3.1 | evolution |
Bacillus methanolicus wild-type strain MGA3 possesses two putative rpe genes encoded on plasmid pBM19 (rpe1-MGA3) and on the chromosome (rpe2-MGA3). The Rpe2-MGA3 enzyme shows a 2fold lower Vmax and a significantly reduced thermostability compared to the Rpe1 protein |
-, 746858 |
| 5.1.3.1 | evolution |
Bacillus methanolicus wild-type strain PB1 possesses one putative rpe gene encoded on plasmid pBM20 (rpe1-PB1) |
-, 746858 |
| 5.1.3.1 | malfunction |
deletion of D-ribulose-5-phosphate 3-epimerase (RPE1) induces simultaneous utilization of xylose and glucose in xylose-utilizing Saccharomyces cerevisiae |
-, 747383 |
| 5.1.3.1 | metabolism |
D-ribulose-5-P 3-epimerase catalyzes the second step of D-ribitol catabolism. The enzyme is probably involved in an alternative ribitol degradation pathway, which might be functional in Lactobacillus casei strain 64H but not in strain BL23, because one of the BL23 genes carries a frameshift mutation |
-, 727770 |
| 5.1.3.1 | metabolism |
D-ribulose-5-phosphate-3-epimerase (RPE) is involved in the ribulose monophosphate (RuMP) cycle in Bacillus methanolicus. Strains MGA3 and PB1 exert alternative solutions to plasmid-dependent methylotrophy, including genetic organization, regulation, and biochemistry of RuMP cycle enzymes, overview |
-, 746858 |
| 5.1.3.1 | metabolism |
the growth condition-dependent enzyme is present in the proteomes of wild-type and zwf strains and is downregulated under mixotrophic growth conditions. Twice the amount of xylulose-5-phosphate is synthesized during the Calvin cycle relative to ribose-5-phosphate in mixotrophical growth, and less epimerase is required for maximal conversion of xylulose-5-phosphate to ribulose-5-phosphate, especially during mixotrophic conditions when exogenously added glucose can contribute additional carbon skeletons to the Calvin cycle intermediates |
701569 |
| 5.1.3.1 | physiological function |
Bacillus methanolicus uses the ribulose monophosphate (RuMP) cycle for methanol assimilation involving the enzyme D-ribulose-5-phosphate-3-epimerase (RPE). RPE catalyses the interconversion between D-xylulose-5-phosphate and D-ribulose-5-phosphate, which is the pentose precursor for nucleotide synthesis. In addition to the RuMP cycle, it is involved in the pentose phosphate pathway (PPP). It is presumably not essential for the metabolism of glucose or mannitol |
-, 746858 |
