EC Number   |
General Information |
Reference |
|---|
    4.3.1.18 | malfunction |
a dsdA mutant is attenuated in virulence |
729822 |
| 4.3.1.18 | malfunction |
dsd-null cells exhibit delay in development and arrest at the early culmination stage. The efficiency of spore formation is considerably reduced in the mutant cells |
-, 747858 |
| 4.3.1.18 | metabolism |
due to its low level of expression and the lack of induction by exogenous D-serine, this dsdA gene does not have any apparent contribution to D-serine utilization in Pseudomonas aeruginosa PAO1. However, a high level of DsdA when overexpressed from a recombinant plasmid is able to support growth on D-serine as the sole source of carbon and nitrogen |
747622 |
| 4.3.1.18 | metabolism |
the enzyme is 460fold and 1700fold more active than D-amino acid oxidase and serine racemase, respectively, in degrading D-Ser. D-Ser dehydrogenase is the primary enzyme responsible for D-Ser decomposition in Dictyostelium discoideum |
-, 747858 |
| 4.3.1.18 | physiological function |
DsdA contributes to virulence within the urinary tract of mice |
729822 |
