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EC Number General Information Commentary Reference
Show all pathways known for 4.2.3.17Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.17metabolism key enzyme in directing pathway flux toward taxol precursors, such as taxadien-5alpha-ol 743935
Show all pathways known for 4.2.3.17Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.17more detailed mechanistic analysis of the biosynthesis of taxadiene by enzyme TXS using a hybrid quantum mechanics-molecular mechanics potential in conjunction with free energy simulation methods, overview. Generation of a free-energy fingerprint for type I terpene synthases. The active-site Trp residue W753 is a key feature of the TXS active-site architecture and stabilizes intermediate cations via Pi-cation interactions 747151
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