EC Number   |
General Information |
Reference |
|---|
  4.2.1.174 | evolution |
diterpene synthases transcriptome analysis of Marrubium vulgare leaves, phylogenetic analysis, overview. CPS1 is a class II diterpene synthase, phylogenetic analysis |
743469 |
| 4.2.1.174 | metabolism |
enzyme CPS1 produces a precursor for marrubiin biosynthesis, pathway overview |
743469 |
| 4.2.1.174 | more |
enzyme CPS1 contains a DIDD functional motif |
743469 |
| 4.2.1.174 | physiological function |
in contrast with previously known diterpene synthases that introduce a hydroxyl group at carbon C-8 of the labdane backbone, the MvCPS1-catalyzed reaction proceeds via oxygenation of an intermediate carbocation at C-9, yielding the bicyclic peregrinol diphosphate. A labdane-type diterpene structure bearing an oxygen functionality at carbon C-9 is characteristic for marrubiin and many of the specialized diterpenoids in the genus Marrubium. Enzyme CPS1 produces a precursor for marrubiin biosynthesis |
743469 |
