EC Number |
General Information |
Reference |
---|
4.1.1.32 | malfunction |
enzyme loss impairs gluconeogenesis from lactate, lowers plasma glucose, insulin, and triglycerides, reduces hepatic glycogen, and increases glycerol turnover |
727993 |
4.1.1.32 | metabolism |
approximately a third of gluconeogenesis comes from the enzyme |
727993 |
4.1.1.32 | physiological function |
one of the important enzymes in the interconversion between C3 and C4 metabolites. It provides phosphoenolpyruvate from oxaloacetate as the first step of gluconeogenesis. The enzyme plays an additional role in the recycling of excess phosphoenolpyruvate produced from pyruvate, replacing the function of the anaplerotic phosphoenolpyruvate carboxylase that is missing from this archaeon |
669085 |
4.1.1.32 | physiological function |
recombinant PEPCK protein exhibits the ability to bind lipopolysaccharide and peptidoglycan, but not beta-1,3-glucan, lipoteichoic acid, mannan nor polyinosinic-polycytidylic. It can also bind Escherichia coli, Staphylococcus aureus and Micrococcus luteus peptidoglycans and significantly inhibit their growth |
747633 |
4.1.1.32 | physiological function |
the enzyme is involved in the initiation of growth, including the induction of amino acid synthesis and energy metabolism |
715782 |