EC Number   |
General Information |
Reference |
|---|
    4.1.1.1 | evolution |
the enzyme is a member of the superfamily of thiamine diphosphate-dependent enzymes |
727679 |
| 4.1.1.1 | malfunction |
deletion of PDC1 results in highly wettable mycelia, deletion of the PDC1 gene results in suppression of GFP-tagged acetyl-coenzyme A synthetase 1 expression |
727549 |
| 4.1.1.1 | malfunction |
deletion of the Ser/Thr protein phosphatase SIT4 phosphatase decreases the pyruvate decarboxylase activity |
-, 727559 |
| 4.1.1.1 | malfunction |
mutations in both PDC1 and PDC2 result in lower tolerance to submergence |
-, 728448 |
| 4.1.1.1 | metabolism |
activities of pyruvate decarboxylase and alcohol dehydrogenase are required for the fermentative pathway, with ethanol as the predominant end product |
-, 728448 |
| 4.1.1.1 | metabolism |
activities of pyruvate decarboxylase and alcohol dehydrogenase are required for the fermentative pathway, with ethanol as the predominant end product. Not only isozyme PDC1 but also isozyme PDC2 play a role under hypoxic conditions. The enzyme has a role under aerobic conditions, which is not coupled to fermentative metabolism |
-, 728448 |
| 4.1.1.1 | metabolism |
pyruvate decarboxylase activity is regulated by the Ser/Thr protein phosphatase Sit4p in the yeast Saccharomyces cerevisiae, mechanism of regulation of pyruvate decarboxylase activity, overview |
-, 727559 |
| 4.1.1.1 | more |
the enzyme forms filamentous structures |
727473 |
| 4.1.1.1 | physiological function |
alpha-ketoisovalerate decarboxylase (kivD), BCAA-specific aminotransferase (bcaT) and C-S lyase (yjtE) gene expressions increase markedly by both isoleucine and valine starvation. Lactococcus lactis IFPL730 growth rate decreases under leucine, valine or isoleucine starvation but the strain reaches similar viable counts at the stationary phase in all culture conditions studied |
-, 736264 |
| 4.1.1.1 | physiological function |
both isoforms PDC1 and PDC2 contribute to anoxia tolerance in Arabidopsis |
728448 |
