EC Number |
General Information |
Reference |
---|
3.6.1.54 | malfunction |
blockage of LpxH causes accumulation of detergent-like pathway intermediates that prevents cell growth |
-, 758137 |
3.6.1.54 | malfunction |
construction of Escherichia coli mutant KB21/pKJB5 that contains a kanamycin cassette inserted into the chromosomal copy of lpxH. The plasmid pKJB5 harbors lpxH+ and features a temperature-sensitive origin of replication. KB21/pKJB5 grows on nutrient medium at 30 °C but not at 44 °C when the plasmid carrying lpxH+ is lost. It is conclude that lpxH is essential in Escherichia coli |
698721 |
3.6.1.54 | malfunction |
enzyme depletion causes clear morphological defects in Acinetobacter baumannii strain ATCC 19606 |
-, 758137 |
3.6.1.54 | malfunction |
UDP-2,3-diacylglucosamine-deficiency results in lethality |
-, 718879 |
3.6.1.54 | metabolism |
the enzyme is involved in lipid A biosynthesis. The enzyme is essential for growth in the strain Acinetobacter baumannii ATCC 19606 |
-, 758137 |
3.6.1.54 | physiological function |
the enzyme is essential for growth in Acinetobacter baumannii strain ATCC 19606 |
-, 758137 |