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Results 1 - 9 of 9
EC Number General Information Commentary Reference
Show all pathways known for 3.6.1.27Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.27malfunction an undecaprenyl pyrophosphate phosphatase null mutant does not show any significant growth or morphological defect, neither is its sensitivity to bacitracin affected. However, the enzyme activity in the mutant is reduced by 75% 718534
Show all pathways known for 3.6.1.27Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.27malfunction enzyme deletion results in a mutant with reduced biofilm formation that is highly sensitive to bacitracin, but confers more resistance to lactococcin G -, 757618
Show all pathways known for 3.6.1.27Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.27malfunction enzyme depletion disrupts cell envelope biogenesis in Bacillus subtilis and leads to morphological defects consistent with a failure of cell envelope synthesis and strongly activates the sigmaM-dependent cell envelope stress response 757099
Show all pathways known for 3.6.1.27Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.27malfunction single uppP or bcrC enzyme deletions show no or less than 0.1% misshaped cells. In contrast, both enzyme depletions leads to a severe phenotype during exponential growth phase 756791
Show all pathways known for 3.6.1.27Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.27physiological function mutants lacking enzymic activity show no significant changes in growth rate, colony morphology and biofilm formation. The mutants exhibit increased susceptibility to bacitracin. When the enzyme is expressed in a wild-type background, the minimum inhibitory concentration of bacitracin increases to 256 mg/L. The minimum inhibitory concentrations of cefoxitin, teicoplanin, vancomycin, gentamicin, enrofloxacin and D-cycloserine are unaltered in the mutant relative to the wild-type, as are susceptibilities to other stress agents such as glycine, lysozyme, NaCl, SDS, low and high pH, oxidative stress and ethanol 734038
Show all pathways known for 3.6.1.27Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.27physiological function the enzyme BcrC is more relevant during vegetative growth while the enzyme UppP is crucial for normal sporulation. Together, enzyme forms bcrC and uppP encode the essential undecaprenyl diphosphatase function of Bacillus subtilis 756791
Show all pathways known for 3.6.1.27Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.27physiological function the enzyme confers resistance to bacitracin 718534
Show all pathways known for 3.6.1.27Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.27physiological function the enzyme is essential in vivo for stomach colonization and is also involved in cationic antimicrobial peptide resistance -, 758199
Show all pathways known for 3.6.1.27Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.27physiological function the enzyme plays important roles in cell wall biosynthesis and bacitracin resistance -, 757618
Results 1 - 9 of 9