EC Number   |
General Information |
Reference |
|---|
  3.5.1.128 | malfunction |
Arabidopsis nit1 knockout lines display a loss in the production of deaminated glutathione with accumulation of higher levels of the glutathione breakdown products cysteinylglycine and cystathionine |
752724 |
| 3.5.1.128 | physiological function |
ablating the Arabidopsis Nit1 gene causes a massive accumulation of N-(4-oxoglutaryl)-L-cysteinylglycine and other marked changes to the metabolome |
752728 |
| 3.5.1.128 | physiological function |
deaminated glutathione, i.e. N-(4-oxoglutaryl)-L-cysteinylglycine, is exreted in large amounts in the urine of Nit1 knock-out mice |
746322 |
| 3.5.1.128 | physiological function |
Nit1-KO mutant cells accumulate deaminated GSH |
746322 |
| 3.5.1.128 | physiological function |
the enzyme functions as a metabolite repair enzyme that removes deaminated glutathione from the cytoplasm and plastids |
752724 |
| 3.5.1.128 | physiological function |
the N-(4-oxoglutaryl)-L-cysteinylglycine repair system is directed to at least two cellular compartments (cytoplasm, plastid) via the use of alternative translation start sites |
752728 |
