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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 3.5.1.125physiological function the degradation of ectoine proceeds via hydrolysis of ectoine by DoeA to Nalpha-acetyl-L-2,4-diaminobutanoate, followed by deacetylation to diaminobutanoate by DoeB and a transaminase reaction by DoeD leading to aspartate-semialdehyde. Deletion of doeB result in a mutant that cannot utilize ectoine as carbon and nitrogen source. Nalpha-acetyl-L-2,4-diaminobutanoate accumulates as the predominant amino-reactive solute in the mutant while no Nalpha-acetyl-L-2,4-diaminobutanoate is detectable in the wild type -, 740379
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