EC Number |
General Information |
Reference |
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3.4.24.85 | malfunction |
after heat treatment at 44°C, the enzyme knockout mutant cannot grow at all, whereas the wild type recovers from thermal damage quickly |
754665 |
3.4.24.85 | malfunction |
an enzyme knockout mutant is more sensitive to 120 mM ammonium chloride than the wild type |
754667 |
3.4.24.85 | malfunction |
enzyme gene ablation is compatible with parasite replication and stage conversion but results in reduced parasite development in late liver stages and in the asexual intra-erythrocytic cycle |
755137 |
3.4.24.85 | metabolism |
activation of the extracytoplasmic function sigma factor sigmaP by beta-lactams in Bacillus thuringiensis requires the site-2 protease RasP |
-, 754811 |
3.4.24.85 | physiological function |
cells defective in the site-2 protease gene have remarkably higher level of superoxide and elevated rates of cell death than wild-type CHO cells. Lack of the site-2 proease gene leads to cells more vulnerable to oxidative stress. Compared with wild-type CHO cells, mutant cells have higher nicotinamide adenine dinucleotide phosphate oxidase activity and lower paraoxonase-2 expression |
735261 |
3.4.24.85 | physiological function |
gene product is essential for growth. A partially segregated mutant displays defective acid acclimation to pH 6.5. Early acid acclimation to pH 6.5 in the wild-type strain includes upregulation of sigH, hik16 and hik35 and downregulation of pcrR and sigG, as well as downregulation of porins and upregulation of inorganic carbon and nitrogen transporters. The inability of the mutant strain to survive at pH 6.5 is related to defective photosynthesis and excess expression of NADH dehydrogenase, together with excessive upregulation of carbon transporter and repression of nitrogen transporter and metabolism genes. Slr0643 disruption and expression of the sigH operon are closely related |
734641 |
3.4.24.85 | physiological function |
HurP is essential for heme-dependent induction of bhuR and downstream genes |
710497 |
3.4.24.85 | physiological function |
knock-out of sll0528 gene increases Synechocystis sp. PCC 6803 sensitivity to salt, cold and hyperosmotic stress, as revealed by retarded growth, reduced pigments and disrupted photosystems |
734002 |
3.4.24.85 | physiological function |
loss-of-function mutant confers high sensitivity to abscisic acid during seed germination. Site-2 protease desensitizes abscisic acid signaling during seed germination through regulating the activation of the membrane-associated transcription factor bZIP17 and therefore controlling the expression level of genes encoding negative regulators of abscisic acid signaling |
734789 |
3.4.24.85 | physiological function |
RasP is involved in transmembrane stress signal transduction |
720919 |