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EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.35physiological function cysteine proteinase 5 is a major virulent factor that binds integrin on colonic cells and stimulates nuclear factor kappaB-mediated pro-inflammatory responses. Cysteine proteinase 5 is the critical proteinase involved in activating nuclear factor kappaB, phosphorylating Akt and inducing the ubiquitination of nuclear factor-kappaB essential modulator -, 717810
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.35physiological function Entamoeba histolytica-secreted cysteine proteases induce interleukin-8 production in human mast cells via a protease-activated receptor 2-independent mechanism which contributes to interleukin-8-mediated tissue inflammatory responses during the early phase of human amoebiasis 732605
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.35physiological function the enzyme is highly involved in the virulence of Entamoeba histolytica 731356
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