EC Number   |
General Information |
Reference |
|---|
   3.4.21.84 | metabolism |
factor C is involved in the LPS reactive coagulation cascade system in the Limulus horseshoe crab that results in the formation of a coagulin gel |
754261 |
| 3.4.21.84 | metabolism |
the enzyme is part of the clotting cascade of Limulus polyphemus. Factor C, the first component of the cascade, is a serine protease that is activated by endotoxin binding. The cascade, initiated by lipopolysaccharide, culminates in the activation of the pro-clotting enzyme to its active form, the clotting enzyme, which in turn acts on coagulogen to convert it into the coagulin clot |
754404 |
| 3.4.21.84 | physiological function |
Factor C activates factor B in the clotting cascade in Limulus polyphemus |
754261, 754404 |
| 3.4.21.84 | physiological function |
RNAi silencing results in a significant reduction in phagocytic activity of tick hemocytes against the Gram-negative bacteria Chryseobacterium indologenes and Escherichia coli, but not against the yeast, Candida albicans |
731699 |
