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EC Number General Information Commentary Reference
Show all pathways known for 3.1.5.1Display the word mapDisplay the reaction diagram Show all sequences 3.1.5.1metabolism blockage of the alternative dUMP phosphatase pathway for deoxyribose-1-phosphate generation greatly exacerbates the severity of thymine starvation in enriched media, and under these conditions the dgt pathway becomes crucial in protecting the cells against thymineless death 716268
Show all pathways known for 3.1.5.1Display the word mapDisplay the reaction diagram Show all sequences 3.1.5.1physiological function the minimal amount of thymine required for growth of thymine-requiring (thyA) strains decreases with increased expression level of the dgt gene. As expected, this dgt-mediated effect is dependent on the DeoD purine nucleoside phosphorylase. ThyA strains experience growth difficulties upon nutritional shift-up, the dgt gene facilitates adaptation to the new growth conditions 716268
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