Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search General Information

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 6 of 6
EC Number General Information Commentary Reference
Show all pathways known for 3.1.3.18Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.18metabolism cysteine residues Cys35, Cys104 and Cys243 in the catalytic core domain of PGP mediate the reversible inhibition of PGP activity and the associated, redox-dependent conformational changes. Cys35 oxidation weakens van-der-Waals interactions with Thr67, a conserved catalytic residue required for substrate coordination. Cys104 and Cys243 form a redox-dependent disulfide bridge between the PGP catalytic core and cap domains. Cys297 in the PGP cap domain is essential for redox-dependent PGP oligomerization, and PGP oxidation/oligomerization occurs in response to stimulation of cells with EGF 750613
Show all pathways known for 3.1.3.18Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.18physiological function compared with the wild-type, the double mutant 1sll1349/slr0458 shows a 60% decrease in specific growth rates in low CO2-conditions 750673
Show all pathways known for 3.1.3.18Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.18physiological function knockdown of 2-phosphoglycolate phosphatase PGLP leads to distinct signs of the photorespiratory phenotype only below 5% residual PGLP protein. These lines are stunted in growth, have strongly increased 2-phosphoglycolate content, exhibit accelerated leaf senescence, and accumulate high amounts of branched-chain and aromatic amino acids. The ribulose-1,5-bisphosphate regeneration is cumulativly impaired with increased photorespiratory pressure 751227
Show all pathways known for 3.1.3.18Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.18physiological function PGP depletion facilitates fatty acid flux through the intracellular triacylglycerol/fatty acid cycle, and phosphatidylinositol-4,5-bisphosphate is critical for the impact of PGP activity on EGF-induced signaling. Loss of endogenous PGP expression amplifies both EGF-induced EGF receptor autophosphorylation and Src-dependent tyrosine phosphorylation of phospholipase C-gamma1. EGF enhances the formation of circular dorsal ruffles in PGP-depleted cells via Src/PLCgamma1/protein kinase C (PKC)-dependent signaling to the cytoskeleton 749969
Show all pathways known for 3.1.3.18Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.18physiological function protein is essential for parasite survival during asexual stages 751128
Show all pathways known for 3.1.3.18Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.18physiological function replacement of murine Pgp with its phosphatase-inactive PgpD34N mutant is embryonically lethal due to intrauterine growth arrest and developmental delay in midgestation. PGP inactivation attenuates triosephosphate isomerase activity, increases triglyceride levels at the expense of the cellular phosphatidylcholine content, and inhibits cell proliferation. These effects are prevented under hypoxic conditions or by blocking phosphoglycolate release from damaged DNA 752206
Results 1 - 6 of 6