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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 3.1.21.9physiological function the absence of either exonuclease III or endonuclease IV has no effect on survival. Exonuclease III and endonuclease IV are equally able to repair the apurinic-apyrimidinic site created by PD-DNA glycosylase. This apurinic-apyrimidinic site is atypical, since only the 5' glycosyl bond in the dimer is cleaved and the product is a cyclobutane dimer bound to DNA by a single glycosyl bond. Neither T4 endonuclease V nor endonuclease III is required for the repair of these apurinic-apyrimidinic sites 727716
Display the reaction diagram Show all sequences 3.1.21.9physiological function the phage T4 enzyme is involved in degradation of host DNA 134240
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