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Results 1 - 4 of 4
EC Number General Information Commentary Reference
Show all pathways known for 2.7.4.26Display the word mapDisplay the reaction diagram Show all sequences 2.7.4.26malfunction AtIPK knockout or knockdown affects formation of two of the three predominant Arabidopsis sterols. Similar sterol levels in knockout (ipk1) and knockdown (ipk2) mutants indicate that remaining AtIPK expression in ipk2 supports only marginal flux toward IPP/DMAPP formation without increasing downstream terpenoid production relative to the null ipk knockout. The lack of reduction in stigmasterol levels suggests that the reduced pool of sitosterol, the immediate precursor of stigmasterol, is still sufficient to sustain unaltered production of the latter. In addition, emission of beta-caryophyllene, the most abundant sesquiterpene compound in Arabidopsis is reduced by 25-31% in flowers of ipk mutants compared with wild-type 739544
Show all pathways known for 2.7.4.26Display the word mapDisplay the reaction diagram Show all sequences 2.7.4.26metabolism the enzyme is involved in the isopentenyl phosphate kinase pathway. The absence of two components of the mevalonate (MVA) pathway from archaeal genomes leads to the discovery of an alternative mevalonate pathway with isopentenyl phosphate kinase (IPK) catalyzing the final step, the formation of isopentenyl diphosphate. Despite the fact that plants contain the complete classical mevalonate pathway, IPK homologues are identified in every sequenced green plant genome. Position and potential role of IPK in the plant terpenoid metabolic network, overview 739544
Show all pathways known for 2.7.4.26Display the word mapDisplay the reaction diagram Show all sequences 2.7.4.26metabolism the enzyme is involved in the mevalonate pathway forming the building blocks for isoprenoid biosynthesis, overview -, 739681
Show all pathways known for 2.7.4.26Display the word mapDisplay the reaction diagram Show all sequences 2.7.4.26physiological function IPK may be functionally connected to the mevalonate (MVA) pathway and biosynthesis of downstream terpenoids, including sesquiterpenes, triterpenes, and sterols. Enzyme IPK catalyzes the final step in the formation of isopentanyl diphosphate. Plants IPK plays a role in modulating the formation and pool sizes of farnesyl diphosphate-derived terpenoids. IPK also contributes to formation of geranyl diphosphate-derived terpenoids in plastids 739544
Results 1 - 4 of 4