EC Number   |
General Information |
Reference |
|---|
   2.7.1.199 | malfunction |
deletion of the enzyme gene results in resistance to sublancin |
760353 |
| 2.7.1.199 | metabolism |
the phosphoenolpyruvate-dependent glucose phosphotransferase system is the major uptake system responsible for transporting glucose, and is involved in glucose translocation and phosphorylation in Corynebacterium glutamicum |
762512 |
| 2.7.1.199 | physiological function |
as unphosphorylated EIIAGlc, a subunit of the glucose-specific phosphotransferase system (PTS), is generated in the presence of glucose, the PTS thus acts as a sensor of glucose for the carbon storage regulator system. Therefore, EIIAGlc can work as a molecular switch that regulates the carbon storage regulator system in response to glucose |
761932 |
| 2.7.1.199 | physiological function |
EIIAGlc of the glucose-specific PTS system is required for the normal decay of the sRNAs of carbon storage regulators CsrB and CsrC. It acts by binding to the EAL domain of CsrD. Only the unphosphorylated form of EIIAGlc binds to CsrD in vitro and is capable of activating CsrB/C turnover in vivo |
761933 |
| 2.7.1.199 | physiological function |
the enhanced expression of the enzyme is responsible for the uptake of D-glucose, increased succinate production, and fast growth of adapted cells. Under anaerobic conditions the enzyme can play a critical role as a D-glucose transporter in the absence of sugar-PTS system |
761147 |
