EC Number   |
General Information |
Reference |
|---|
    2.7.1.12 | drug target |
gluconokinase IDNK plays a key role in the proliferation and apoptosis of HCC cells. It may be a candidate therapeutic target for hepatocellular carcinoma |
762082 |
| 2.7.1.12 | malfunction |
inactivation of the gluconate kinase gene leads to a 51.8% increase in intracellular NADPH concentration, which results in a 49.9% increase in L-ornithine production |
722889 |
| 2.7.1.12 | metabolism |
6-phosphogluconate dehydrogenase (Gcd1) and gluconate kinase (Idn1) act together to shunt glucose into the pentose phosphate pathway, creating an alternative route for directing glucose into the pentose phosphate pathway that bypasses hexokinase and the rate-limiting enzyme glucose-6-phosphate dehydrogenase |
-, 761462 |
| 2.7.1.12 | metabolism |
pentose phosphate pathway |
696574 |
| 2.7.1.12 | metabolism |
phosphogluconate pathway, bacterial enzyme is active in young, non-inoculated mesquite seedlings growing under hydroponic conditions |
-, 700784 |
| 2.7.1.12 | physiological function |
gluconokinase IDNK promotes cell proliferation and inhibits apoptosis in hepatocellular carcinoma |
762082 |
| 2.7.1.12 | physiological function |
when azospirillum brasilense Cd bacteria are inoculated on the root system, the roots exhibit much higher activity of gluconokinase |
-, 700784 |
