EC Number |
General Information |
Reference |
---|
2.5.1.72 | more |
three strictly conserved amino acids, Glu198, Tyr109, and Tyr23, are in close proximity to the bound product. Substitution of these amino acids with Gln, Phe, and Phe, respectively, leads to complete loss of activity |
738460 |
2.5.1.72 | physiological function |
quinolinate synthase is a Fe4S4 cluster-containing dehydrating enzyme involved in the synthesis of quinolinic acid, the universal precursor of the essential nicotinamide adenine dinucleotide coenzyme |
-, 738452 |
2.5.1.72 | physiological function |
quinolinate synthase is an [4Fe-4S] cluster-containing dehydrating enzyme involved in synthesis of quinolinic acid, the universal precursor of the essential coenzyme nicotinamide adenine dinucleotide |
737716 |
2.5.1.72 | physiological function |
quinolinate synthase is involved in synthesis of quinolinic acid, the universal precursor of the essential coenzyme nicotinamide adenine dinucleotide |
738460 |