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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 2.4.2.53physiological function enzyme participates in the biosynthesis of UDP-4-amino-4-deoxy-L-arabinose from UDP-GlcA in polymyxin-resistant Escherichia coli 698723
Display the reaction diagram Show all sequences 2.4.2.53physiological function enzyme takes part in the biosynthesis of UDP-4-amino-4-deoxy-L-arabinose in polymyxin-resistant Escherichia coli. The N-formylation of UDP-4-amino-4-deoxy-L-arabinose is an obligatory step in the biosynthesis of 4-amino-4-deoxy-L-arabinose-modified lipid A in polymyxin-resistant mutants. Only the formylated sugar nucleotide is converted in vitro to an undecaprenyl phosphate-linked form by the enzyme ArnC. Because the L-Ara4N unit attached to lipid A is not derivatized with a formyl group, a deformylase must be acting later in the pathway 698730
Display the reaction diagram Show all sequences 2.4.2.53physiological function pmrF inactivation in Yersinia pseudotuberculosis has no effect on bacterial virulence in the mouse 709838
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