EC Number |
General Information |
Reference |
---|
2.4.1.357 | evolution |
the enzyme belongs to the UDP-glycosyltransferase UGT88F subfamily, subfamily tree, genomic organization of the UGT88F members on chromosome 15 and 8, overview. UGT88F1 is located closer to UGT88F4 on chromosome 15 and both genes share the same orientation. On chromosome 8, UGT88F6, UGT88F7 and UGT88F8 form a physical cluster sharing the same orientation. The Km values of UGT88F8 are 0.0077 mM and 0.0108 mM for phloretin and UDP-glucose, respectively, and are in the same range as UGT88F1 catalytic parameters thus constituting two isoforms. Co-expression patterns of both UGT88F1 and UGT88F8 argue for a redundant function in phlorizin biosynthesis in planta |
759918 |
2.4.1.357 | evolution |
the enzyme belongs to the UDP-glycosyltransferase UGT88F subfamily, subfamily tree, genomic organization of the UGT88F members on chromosome 15 and 8, overview. UGT88F1 is located closer to UGT88F4 on chromosome 15 and both genes share the same orientation. On chromosome 8, UGT88F6, UGT88F7 and UGT88F8 form a physical cluster sharing the same orientation. The Km values of UGT88F8 are 7.72 microM and 10.84 microM for phloretin and UDP-glucose, respectively, and are in the same range as UGT88F1 catalytic parameters thus constituting two isoforms. Coexpression patterns of both UGT88F1 and UGT88F8 argue for a redundant function in phlorizin biosynthesis in planta |
759918 |
2.4.1.357 | malfunction |
enzyme-knockdown lines are severely dwarfed, with greatly reduced internode lengths, narrow lanceolate leaves, and changes in leaf and fruit cellular morphology |
748955 |
2.4.1.357 | more |
three-dimensional structure analysis, modeling, and structure-function relationship, overview |
759918 |
2.4.1.357 | physiological function |
involvement of the enzyme in phlorizin (i.e. phloridzin or phloretin 2'-O-glucoside) synthesis, the main apple tree dihydrochalcone |
759918 |
2.4.1.357 | physiological function |
involvement of the enzyme in phlorizin (i.e. phloridzin or phloretin 2'-O-glucoside) synthesis, the main apple tree dihydrochalcone. UGT88F1 is able to efficiently glycosylate dihydrochalcones |
759918 |