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Results 1 - 10 of 14 > >>
EC Number General Information Commentary Reference
Show all pathways known for 2.3.1.212Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.212evolution the enzyme is a plant-specific type III polyketide synthase of the chalcone synthase (CHS) superfamily 721184, 721796, 722314, 723327, 723330, 723358
Show all pathways known for 2.3.1.212Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.212evolution the enzyme is a plant-specific type III polyketide synthase of the chalcone synthase (CHS) superfamily, amino acids C164, F215, H303 and N336 are conserved 684699
Show all pathways known for 2.3.1.212Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.212evolution the enzyme is a plant-specific type III polyketide synthase of the chalcone synthase (CHS) superfamily. BAS lacks the critical residue Phe215, that is important in the polyketide formation reactions, structure-function relationship of the plant type III PKSs, overview. The absence of Phe215 in BAS accounts for the interruption of the polyketide chain elongation at the diketide stage 722633
Show all pathways known for 2.3.1.212Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.212evolution the enzyme is a plant-specific type III polyketide synthase of the chalcone synthase (CHS) superfamily. Comparison of the primary sequences and and secondary structures of BAS and other type III PKSs, overview 721798
Show all pathways known for 2.3.1.212Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.212evolution the enzyme is a plant-specific type III polyketide synthase of the chalcone synthase (CHS) superfamily. Members of the CHS-superfamily enzymes do not form a species-specific cluster, but instead group into subfamilies according to their enzymatic function. BAS lacks the active-site Phe215 residue (numbering in CHS), which has been proposed to help orient substrates and intermediates during the sequential condensation of 4-coumaroyl-CoA with malonyl-CoA in CHS, while the catalytic cysteine-histidine dyad (Cys164-His303) in CHS is well conserved in BAS 722174
Show all pathways known for 2.3.1.212Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.212more pH-dependence of benzalacetone and bisnoryangonin production. Residues Ile214 and Leu215 are responsible for the diketide formation activity, unlike the case of CHS with residues L214 and F215, BAS utilizes an alternative pocket to lock the coumaroyl moiety for the diketide formation reaction, the second active-site Cys is not involved in the enzyme reaction,and Cys197 is not essential for the 4-hydroxybenzalacetone-producing activity, homology modeling 721796
Show all pathways known for 2.3.1.212Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.212more structure-function relationship, homology modeling, overview 721798
Show all pathways known for 2.3.1.212Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.212more structure-function relationship, overview 721184
Show all pathways known for 2.3.1.212Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.212more the absence of Phe215 in BAS accounts for the interruption of the polyketide chain elongation at the diketide stage compared to chalcone synthase, EC 2.3.1.74, structure-function relationship , overview. BAS catalytic residues are Asn336, His303, and Cys164, active site structure, overview 722633
Show all pathways known for 2.3.1.212Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.212physiological function 4-hydroxybenzalacetone, i.e. 4-hydroxyphenylbutan-2-one, the characteristic aroma compound of raspberries, is synthesized from 4-coumaryl-CoA and malonyl-CoA in a two-step reaction sequence that is catalyzed by benzalacetone synthase and benzalacetone reductase. 4-Hydroxybenzalacetone inhibits mycelial growth of the raspberry pathogen Phytophthora fragariae var. rub -, 723451
Results 1 - 10 of 14 > >>