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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 2.3.1.187metabolism to achieve decarboxylation of malonate, the key reaction in the decomposition of this compound, the substrate must be activated by the malonate decarboxylase to a malonyl thio-enzyme ester involving an activation module that comprises the acetylation of a specific thiol group of an acyl carrier protein, ACP, and the transfer of the ACP moiety to malonate, yielding malonyl-S-ACP and acetate. The malonyl-S-ACP is subsequently decarboxylated with regeneration of the acetyl-ACP. Malonate decarboxylation pathway, overview 718124
Display the reaction diagram Show all sequences 2.3.1.187more the acetyl-S-ACP:malonate ACP transferase is a component of the malonate decarboxylase complex 718124
Display the reaction diagram Show all sequences 2.3.1.187more the acetyl-S-acyl carrier protein:malonate acyl carrier protein-SH transferase is a component of the malonate decarboxylase complex 718124
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