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EC Number	General Information	Commentary	Reference
2.1.1.372	physiological function	Set9 is responsible for histone H4K20 methylation in Schizosaccharomyces pombe. H4K20 methylation does not have any apparent role in the regulation of gene expression or heterochromatin function but the modification has a role in DNA damage response. Loss of Set9 activity or mutation of H4K20 markedly impairs cell survival after genotoxic challenge and compromises the ability of cells to maintain checkpoint mediated cell cycle arrest	-, 756362

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Release 2023.1 (January 2023)