EC Number |
General Information |
Reference |
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2.1.1.325 | malfunction |
dietary introduction of dsJHAMT1 and dsJHAMT2 successfully knock down the target gene, lower juvenile hormone titre in the haemolymph and reduce the transcript of Krüppel homologue 1 gene. Ingestion of dsJHAMT cause larval death and weight loss, shorten larval developmental period and impaire pupation. The JHAMT-fed pupae exhibit lower adult emergence rates. The resulting adults weighed an average of 50 mg less than the control group, and the females did not deposit eggs |
757917 |
2.1.1.325 | malfunction |
inhibition of enzyme transcription leads to inhibition of egg maturation and larval development |
738813 |
2.1.1.325 | malfunction |
RNAi-triggered knock down of the enzyme (JHAMT) produces an extremely high reduction of synthesis of the juvenile hormone, concomitant with a decrease of fat body vitellogenin expression and basal follicle length |
756917 |
2.1.1.325 | metabolism |
the enzyme has little if any effect on sesquiterpenoid biosynthesis |
739244 |
2.1.1.325 | physiological function |
enzyme overexpression results in a pharate adult lethal phenotype suggesting that the temporal regulation of the enzyme is critical for Drosophila development |
738377 |
2.1.1.325 | physiological function |
nutrition and its signaling through the insulin receptor and TOR pathways are essential for activating enzyme (JHAMT) expression, which suggests that this enzyme can be a checkpoint for the regulation of juvenile hormone production in relation to nutritional status |
756917 |
2.1.1.325 | physiological function |
the enzyme has a measurable role on the fertility |
737562 |
2.1.1.325 | physiological function |
the enzyme is actively involved within larval development, metamorphosis and adult reproduction of Holcocerus hippophaecolus |
738112 |
2.1.1.325 | physiological function |
the enzyme is essential for juvenile hormone biosynthesis and for the maintenance of larval status |
738201 |
2.1.1.325 | physiological function |
the enzyme is important for the regulation of eyestalk neuropeptides |
738375 |