EC Number   |
General Information |
Reference |
|---|
    2.1.1.295 | evolution |
the cultivated peanut Arachis hypogaea might originate via hybridization of Arachis duranensis (A-genome) and Arachis ipaensis (B-genome), followed by a rare spontaneous duplication of chromosomes, phylogenetic analysis |
736187 |
| 2.1.1.295 | evolution |
the enzyme has the typical functional domains of an SAM enzyme |
756491 |
| 2.1.1.295 | malfunction |
an SLL0418 partial knockout mutant accumulates beta-tocopherol with no effect in the overall tocopherol content of the cell |
724991 |
| 2.1.1.295 | metabolism |
2-methyl-6-phytyl-1,4-benzoquinol methyltransferase (MPBQ-MT) is a vital enzyme catalyzing a key methylation step in both alpha/gamma-tocopherol and plastoquinone biosynthetic pathway |
758129 |
| 2.1.1.295 | metabolism |
2-methyl-6-phytyl-1,4-benzoquinol methyltransferase is one of the critical enzymes involved in vitamin E biosynthesis in plants. The enzyme can catalyze 2-methyl-6-phytyl-1,4-benzoquinol to generate 2,3-dimethyl-6-phytyl-1,4-benzoquinone. Both compounds are cyclized by tocopherol cyclase to yield delta- and gamma-tocopherol, respectively, which are subsequently further converted to beta- and alpha-tocopherol by gamma-tocopherol methyltransferase |
736187 |
| 2.1.1.295 | metabolism |
the enzyme is involved in regulation and biosynthesis of vitamin E in safflower |
756491 |
| 2.1.1.295 | physiological function |
2-methyl-6-phytyl-1,4-benzoquinol methyltransferase (MPBQ-MT) is a vital enzyme catalyzing a key methylation step in both alpha/gamma-tocopherol and plastoquinone biosynthetic pathway. Overexpression of LsMT significantly increases plastoquinone (PQ) level in lettuce. The increase of tocopherol and plastoquinone levels by LsMT overexpression conduce to the improvement of plants' tolerance and photosynthesis under high light stress, by directing excessive light energy toward photosynthetic production rather than toward generation of more photooxidative damage. No significant difference in the expression levels of HPPD, HPT, TC and gamma-TMT is observed between wild-type and transgenic plants, indicating that overexpression of LsMT does not impact on the expression of other genes up- and downstream in the tocopherol biosynthetic pathway. Mechanism by which overexpression of MPBQ-MT leads to enhanced photosynthesis and tolerance to photodamage under high light in lettuce, overview |
758129 |
| 2.1.1.295 | physiological function |
an isoform MT-1 homozygous mutant is non-lethal and produces 24-45% alpha-tocopherol and 55-74% beta-tocopherol as compared to 96% alpha- and 4% beta-tocopherol for wild-type |
728823 |
| 2.1.1.295 | physiological function |
isoform MT-2 compensates for the loss of isoform MT-1 function, and the MT-2 mutation profoundly affects the synthesis of tocopherols without adversely affecting the synthesis of plastoquinone crucial for normal plant growth and development |
728823 |
| 2.1.1.295 | physiological function |
loss of enzymic activity results in accumulation of delta-tocopherol and decreased gamma-tocopherol content in the seed |
728472 |
