EC Number |
General Information |
Reference |
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2.1.1.212 | evolution |
a synteny block among Cicer arietinum chromosome 6 (inverted), Glycyrrhiza uralensis scaffold 00721 and Medicago truncatula chromosome 4, which includes genes involved in isoflavonoid biosynthesis (7-IOMT, CYP93C and HI4OMT), overview |
758013 |
2.1.1.212 | metabolism |
2,7-dihydroxy-4'-O-methoxy-isoflavanone is converted to formononetin, calycosin and calycosin-7-O-beta-D-glucoside via a series of reactions in the calycosin-7-O-beta-D-glucoside pathway. The 2,7,4'-trihydroxyisoflavanone is probably more easily caught by 2-hydroxyisoflavanone 4'-O-methyltransferase and hence provides more precursors for formononetin than being converted to daidzein, overview |
720628 |
2.1.1.212 | metabolism |
the enzyme is involved in the isoflavonoid biosynthesis together with 2-hydroxyisoflavanone synthase (CYP93C) and isoflavone-7-O-methyltransferase (7-IOMT), forming a cluster on the scaffold of the liquorice genome. The second gene in the cluster encodes the enzyme 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase/isoflavone 4'-O-methyltransferase, i.e. HI4OMT (ECs 2.1.1.212 and 2.1.1.46), which typically converts daidzein to formononetin or genistein to biochanin A |
758013 |