EC Number   |
General Information |
Reference |
|---|
   1.8.4.16 | malfunction |
enzyme absence enhances the sensitivity of the dsbA1A2 mutant to oxidative stress |
-, 757694 |
| 1.8.4.16 | malfunction |
enzyme loss leads to hypersensitivity to dithiothreitol and benzylpenicillin |
756583 |
| 1.8.4.16 | metabolism |
cytoplasmic electrons donated by thioredoxin are transferred into the periplasm via the enzyme |
757691 |
| 1.8.4.16 | metabolism |
the enzyme accepts electrons from cytoplasmic thioredoxin and shuttles these electrons via a well-defined cascade through the membrane-spanning region and into the periplasm |
757092 |
| 1.8.4.16 | metabolism |
the enzyme generates a reducing source in the periplasm, which is required for maintaining proper redox conditions |
756583 |
| 1.8.4.16 | metabolism |
the enzyme is a reductase that acts as an electron hub, translocating reducing equivalents from cytoplasmic thioredoxin to a number of periplasmic substrates involved in oxidative protein folding, cytochrome c maturation and oxidative stress defence |
-, 755729 |
| 1.8.4.16 | metabolism |
the enzyme is involved only in cytochromexa0c biogenesis |
756586 |
| 1.8.4.16 | metabolism |
the enzyme is required to maintain the functional oxidation state of DsbC and DsbG |
758258 |
| 1.8.4.16 | metabolism |
the enzyme mediates electron transfer from the cytoplasm across the membrane |
757131 |
| 1.8.4.16 | metabolism |
the enzyme transfers reducing potential to periplasmic protein disulfide bond isomerases and to the cytochromexa0c thioreduction pathway |
756586 |
