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EC Number General Information Commentary Reference
Show all pathways known for 1.3.1.34Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.34malfunction the gene disruption of fadH, which 2,4-dienoyl-CoA reductase, impairs production of eicosapentaenoic acid under docosahexaenoic acid-supplemented conditions, and the estimated conversion rate decreases by 86% compared to that of the parent strain -, 763076
Show all pathways known for 1.3.1.34Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.34physiological function DECR is the major reductase involved in polyunsaturated fatty acid beta-oxidation. DECR is related to bacterial reductases. A DECR null mutant is unable to catabolize unsaturated fatty acids and accumulates the intermediate 2,4-decadienoyl-CoA. The mutant is unable to survive in macrophages and is avirulent in BALB/c mice 759709
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