EC Number   |
General Information |
Reference |
|---|
    1.23.5.1 | evolution |
nucleotide diversity analysis of VDE1 in maize and teosinte indicates that its exon has less genetic variation, consistent with the conserved function of VDE1 in plants. In addition, dramatically reduced nucleotide diversity, fewer haplotypes and a significantly negative parameter deviation for Tajima's D test of ZmVDE1 in maize and teosinte suggest that a potential selective force has acted across the ZmVDE1 locus. A 4.2 Mb selective sweep with low recombination surrounding the ZmVDE1 locus has resulted in severely reduced nucleotide diversity on chromosome 2. Natural selection and the conserved domains of ZmVDE1 might show an important role in the xanthophyll cycle of the carotenoid biosynthesis pathway. Maize domestication involves a radical phenotypic transformation, resulting in an unbranched plant with numerous exposed seed attached to a cob in 20 rows or more. The dramatic morphological changes from teosinte to maize likely involved alterations in only a few significant genes with large effect. Evolution of the ZmVDE1 locus in maize and teosinte, overview |
744970 |
| 1.23.5.1 | evolution |
the four putative activation residues D98, D117, H168 and D206 play are all conserved in plants but not in diatoms |
726294 |
| 1.23.5.1 | evolution |
the violaxanthin cycle: under strong light conditions, enzyme violaxanthin de-epoxidase catalyses de-epoxidation of violaxanthin (Vx) to zeaxanthin via antheraxanthin as an intermediate product. This type of the cycle exists in higher plants, ferns, mosses and some group of algae |
723818 |
| 1.23.5.1 | malfunction |
a reduction in enzyme expression results in greater photosensitivity |
728500 |
| 1.23.5.1 | malfunction |
mutational reduction of the disulfides in the enzyme results in loss of a rigid structure and a decrease in thermal stability of 15°C |
745983 |
| 1.23.5.1 | metabolism |
natural selection and the conserved domains of ZmVDE1 might show an important role in the xanthophyll cycle of the carotenoid biosynthesis pathway |
744970 |
| 1.23.5.1 | metabolism |
the xanthophyll cycle is an important photoprotective process functioning in plants. One of its forms, the violaxanthin cycle, involves interconversion between violaxanthin, antheraxanthin, and zeaxanthin |
723818 |
| 1.23.5.1 | more |
enzyme VDE is active in its completely oxidized form presenting six disulfide bonds. Redox titration show that VDE activity is sensitive to variation in redox potential, suggesting the possibility that dithiol/disulfide exchange reactions may represent a mechanism for VDE regulation |
744904 |
| 1.23.5.1 | more |
molecular dynamics and simulations, overview |
726294 |
| 1.23.5.1 | more |
VDE enzyme activity is possible without the C-terminal domain but not without the N-terminal domain. The N-terminal domain shows no VDE activity by itself, but when separately expressed domains are mixed, VDE activity is possible |
745996 |
