EC Number   |
General Information |
Reference |
|---|
   1.14.20.6 | evolution |
the enzyme belongs to the 2-oxoglutarate iron-dependent oxygenase family |
725927 |
| 1.14.20.6 | evolution |
the enzyme belongs to the 2-oxoglutarate-dependent dioxygenase family |
725178 |
| 1.14.20.6 | evolution |
the enzyme belongs to the the 2-oxoglutarate-Fe(II) dioxygenase superfamily |
726524 |
| 1.14.20.6 | malfunction |
gene FLS silencing reduces the flavonol content by 17-53%, while it increases catechin and epicatechin content 51-93% and 18-27%, respectively. The silenced lines show a significant increase in expression of genes for dihydroflavonol reductase and anthocyanidin synthase, a downstream gene towards epicatechin production, with no significant change in expression of other genes of the flavonoid pathway, phenotypes, overview |
726127 |
| 1.14.20.6 | malfunction |
gene FLS1 silencing reduces the flavonol content by 17-53%, while it increases catechin and epicatechin content 51-93% and 18-27%, respectively. The silenced lines show a significant increase in expression of genes for dihydroflavonol reductase and anthocyanidin synthase, a downstream gene towards epicatechin production, with no significant change in expression of other genes of the flavonoid pathway, phenotypes, overview |
726127 |
| 1.14.20.6 | malfunction |
post-transcriptional silencing of flavonol synthase mRNA in tobacco leads to fruits with arrested seed set, FLS silenced lines show 20-80% reduction in FLS encoding gene expression and 25-93% reduction in quercetin content, as well as a reduction in anthocyanidins content. Content of flavan-3-ols, i.e. catechin, epi-catechin and epigallocatechin, is increased in the transgenic lines, phenotypes, overview |
726287 |
| 1.14.20.6 | malfunction |
post-transcriptional silencing of flavonol synthase mRNA in tobacco leads to fruits with arrested seed set, FLS1 silenced lines show 20-80% reduction in FLS1 encoding gene expression and 25-93% reduction in quercetin content, as well as a reduction in anthocyanidins content. Content of flavan-3-ols, i.e. catechin, epi-catechin and epigallocatechin, is increased in the transgenic lines, phenotypes, overview |
726287 |
| 1.14.20.6 | malfunction |
second functional flavonol synthase fls3 in case of fls1 mutant lines, lacking the active flavonol synthase |
697947 |
| 1.14.20.6 | malfunction |
the anthocyanin level of fls1-3 knock-out mutants is about two-fold higher than that of wild-type seedlings |
743505 |
| 1.14.20.6 | metabolism |
flavonol synthase is key enzyme in the flavonol biosynthetic pathway |
743874 |
