EC Number   |
General Information |
Reference |
|---|
   1.14.19.22 | evolution |
in plants, membrane-bound fatty acid desaturases are present in the plastid and the endoplasmic reticulum. The electron donors for plastid desaturases are typically ferredoxins, while endoplasmic reticulum enzymes use cytochrome b5 (Cytb5) |
745739 |
| 1.14.19.22 | malfunction |
combinations of mutations in FAD2-1A and FAD2-1B produce high oleic acid levels in the seed oil |
724673 |
| 1.14.19.22 | malfunction |
the disruption of the tauDELTA12des in Thraustochytrium aureum by homologous recombination results in the accumulation of oleic acid and a decrease in the levels of linoleic acid and its downstream polyunsaturated fatty acids. The transformation of the tauDELTA 12des -disruption mutants with a tauDELTA 12des expression cassette restores the wild-type fatty acid profiles |
-, 725657 |
| 1.14.19.22 | malfunction |
the increased oleate level in unexpanded leaves due to enzyme-silencing recedes significantly in fully expanded leaves |
734553 |
| 1.14.19.22 | malfunction |
the low protein density in fad2-deficient mitochondrial membranes is mainly responsible for the reduction in proton leak |
734139 |
| 1.14.19.22 | malfunction |
the PI 283327 FAD2-1B allele, carrying the mutant FAD2-1B P137R allele, is associated with an increase in seed oleic acid content. Although the FAD2-1B mutant alleles alone are not capable of producing a high oleic acid phenotype. When existing FAD2-1A mutations are combined with the novel mutant FAD2-1B alleles, a high oleic acid phenotype is recovered only for those lines which are homozygous for both of the mutant alleles |
724673 |
| 1.14.19.22 | malfunction |
transgenic Korean rapeseed Tammi containing high oleic acid contents (78 mol%) are developed via the expression of the BrFAD2-1 gene in an antisense orientation |
726147 |
| 1.14.19.22 | malfunction |
transgenic lines expressing an antisense CsFAD2 gene show a high increase in 18:1 content from 13-18% in wild type to 38-51% in transgenic seeds, and concomitantly significant decrease in 18:2 and 18:3 PUFAs. The levels of eicosenoic acid (20:1), another major monounsaturated fatty acid in camelina seed, are also slightly increased in transgenic seeds. These results clearly indicate that CsFAD2 genes encode microsomal oleate desaturases and contribute to PUFA synthesis in camelina seeds |
726196 |
| 1.14.19.22 | malfunction |
transgenic lines expressing an antisense CsFAD2 genes show a high increase in 18:1 content from 13-18% in wild type to 38-51% in transgenic seeds, and concomitantly significant decrease in 18:2 and 18:3 PUFAs. The levels of eicosenoic acid (20:1), another major monounsaturated fatty acid in camelina seed, are also slightly increased in transgenic seeds. These results clearly indicate that CsFAD2 genes encode microsomal oleate desaturases and contribute to PUFA synthesis in camelina seeds |
726196 |
| 1.14.19.22 | metabolism |
the enzyme is involved in providing polyunsaturated phosphatidylcholine to the chloroplast envelope |
734120 |
