EC Number   |
General Information |
Reference |
|---|
    1.14.19.21 | malfunction |
silencing of PmNvd transcript in shrimp by specific double-stranded RNA (dsNvd) leads to prolonged molt duration with abnormal molting progression, i.e. the molting process got stuck at early premolt stage. In addition, the 20-hydroxyecdysone titer in hemolymph of dsNvd-injected shrimps is significantly reduced compared with that in NaCl-injected shrimps. Phenotype, overview |
744745 |
| 1.14.19.21 | metabolism |
the cholesterol 7,8-dehydrogenase catalyzes the first step of the ecdysteroid biosynthesis converting cholesterol to 7-dehydrocholesterol |
744745 |
| 1.14.19.21 | physiological function |
function of the enzyme in the molting process and molt regulation, crucial role of PmNvd in molt progression, particularly during the initiation of premolt phase via the regulation of ecdysteroid production |
744745 |
| 1.14.19.21 | physiological function |
the enzyme regulates DAF-12 activities for reproductive development and longevity by controlling dafachronic acids production |
723904 |
