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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 1.14.13.211metabolism RIFMO catalyzes the hydroxylation of rifampicin at the C2 atom followed by cleavage of the ansa linkage, which leads to inactivation of the antibiotic by preventing key contacts with the RNA polymerase target -, 764146
Display the reaction diagram Show all sequences 1.14.13.211physiological function the enzyme from Rhodococcus equi has the ability to inactivate the antibiotic rifampicin via its decomposition and confers low-level rifampin resistance -, 735440
Display the reaction diagram Show all sequences 1.14.13.211physiological function the rox gene is capable of initiating rifampicin degradation with another metabolite formation at the first step and having a role as the secondary rifampicin resistance factor in Nocardia farcinica -, 734035
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